C4B63_16g131 – TrypsnetDB2

C4B63_16g131

conserved hypothetical protein

Trypanosoma cruzi Dm28c 2018 OG6: OG6_172095 OG7: OG7_0037545 14 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 14 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_16g290 mitochondrial RNA binding protein	—	OG6 TCSYLVIO_000124 ↔ TCSYLVIO_000195 OG7 TCSYLVIO_000124 ↔ TCSYLVIO_000195	Both
C4B63_18g138 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_003361 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_003361	Both
C4B63_22g162 cysteine peptidase, Clan CA, family C2	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_007343	OG6
C4B63_39g344 ⚠ 14-3-3 protein 1	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_009211 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_009211	Both
C4B63_11g45 ⚠ Metallocarboxypeptidase 1	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_006376 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_006376	Both
C4B63_6g235 ⚠ X-pro, dipeptidyl-peptidase,serine peptidase,	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_002659 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_002659	Both
C4B63_6g396 ⚠ X-pro, dipeptidyl-peptidase,serine peptidase,	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_002659 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_002659	Both
C4B63_2g445 ⚠ Metallocarboxypeptidase 1	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_006376 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_006376	Both
C4B63_70g63 seryl-tRNA synthetase	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_001717 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_001717	Both
C4B63_282g14 ⚠ X-pro, dipeptidyl-peptidase,serine peptidase,	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_002659 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_002659	Both
C4B63_2g446 ⚠ Metallocarboxypeptidase 1	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_006376 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_006376	Both
C4B63_70g95 ⚠ 14-3-3 protein 2	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_009211 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_009211	Both
C4B63_10g166 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_004311 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_004311	Both
C4B63_10g165 ⚠ conserved hypothetical protein	—	OG6 TCSYLVIO_000195 ↔ TCSYLVIO_004311 OG7 TCSYLVIO_000195 ↔ TCSYLVIO_004311	Both

Orthogroup expansion — connections between the query proteins

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