C4B63_11g45

Metallocarboxypeptidase 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105939 OG7: OG7_0011443 44 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 44 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_40g26 ⚠
bromodomain-containing protein 3
— OG7
C4B63_30g231 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
C4B63_16g290 ⚠
mitochondrial RNA binding protein
— Both
C4B63_18g138 ⚠
UV excision repair RAD23-like protein
— Both
C4B63_70g63 ⚠
seryl-tRNA synthetase
— Both
C4B63_10g166 ⚠
conserved hypothetical protein
— Both
C4B63_10g165 ⚠
conserved hypothetical protein
— Both
C4B63_16g131 ⚠
conserved hypothetical protein
— Both
C4B63_30g238 ⚠
conserved hypothetical protein
— Both
C4B63_170g15 ⚠
aminopeptidase
— Both
C4B63_46g74 ⚠
aminopeptidase
— Both
C4B63_57g96 ⚠
bromodomain protein
— Both
C4B63_63g19 ⚠
Bromodomain factor 1
— OG7
C4B63_25g968c ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_34g156 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_181g13 ⚠
conserved hypothetical protein
— OG7
C4B63_7g1820c ⚠
acyl-CoA binding protein
— OG7
C4B63_109g69 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_61g73 ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_41g246 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
C4B63_41g245 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
C4B63_23g83 ⚠
Aminopeptidase M1
— OG7
C4B63_39g344 ⚠
14-3-3 protein 1
— Both
C4B63_173g51 ⚠
beta tubulin
— OG6
C4B63_463g2 ⚠
beta tubulin
— OG6
C4B63_51g125 ⚠
beta tubulin
— OG6
C4B63_333g16 ⚠
beta tubulin
— OG6
C4B63_22g172 ⚠
beta tubulin
— OG6
C4B63_333g21 ⚠
beta tubulin
— OG6
C4B63_333g14 ⚠
beta tubulin
— OG6
C4B63_51g127 ⚠
beta tubulin
— OG6
C4B63_279g12 ⚠
beta tubulin
— OG6
C4B63_22g162 ⚠
cysteine peptidase, Clan CA, family C2
— OG6
C4B63_333g12 ⚠
beta tubulin
— OG6
C4B63_27g1 ⚠
acyl-CoA binding protein
— Both
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_70g95 ⚠
14-3-3 protein 2
— Both
C4B63_122g18 ⚠
acyl-CoA binding protein
— Both
C4B63_38g63 ⚠
conserved hypothetical protein
— Both
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_6g396 ⚠
X-pro, dipeptidyl-peptidase,serine peptidase,
— Both
C4B63_282g14 ⚠
X-pro, dipeptidyl-peptidase,serine peptidase,
— Both
C4B63_6g235 ⚠
X-pro, dipeptidyl-peptidase,serine peptidase,
— Both
C4B63_54g179 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.