C4B63_46g74

aminopeptidase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100948 OG7: OG7_0001210 38 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 38 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_128g64 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_134g60 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_8g483 ⚠
asparagine synthetase a
— OG7
C4B63_2g752 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— OG7
C4B63_22g59 ⚠
cytidine triphosphate synthase
— OG7
C4B63_80g21 ⚠
Nucleoside diphosphate kinase
— OG7
C4B63_47g72 ⚠
enolase
— OG7
C4B63_24g215 ⚠
methyltransferase domain containing protein
— OG7
C4B63_128g65 ⚠
prolyl oligopeptidase
— OG7
C4B63_40g26 ⚠
bromodomain-containing protein 3
— OG7
C4B63_35g155 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_6g564 ⚠
oligopeptidase B-like protein
— OG7
C4B63_122g16 ⚠
oligopeptidase b
— OG7
C4B63_128g66 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_63g19 ⚠
Bromodomain factor 1
— OG7
C4B63_25g317 ⚠
threonine synthase
— OG7
C4B63_303g16 ⚠
trypanothione reductase
— OG7
C4B63_14g241 ⚠
trypanothione reductase
— OG7
C4B63_57g96 ⚠
bromodomain protein
— Both
C4B63_30g231 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
C4B63_41g205 ⚠
alanine aminotransferase
— Both
C4B63_41g203 ⚠
alanine aminotransferase
— Both
C4B63_63g37 ⚠
oligopeptidase b(fragment)
— Both
C4B63_11g45 ⚠
Metallocarboxypeptidase 1
— Both
C4B63_2g445 ⚠
Metallocarboxypeptidase 1
— Both
C4B63_2g553 ⚠
Programmed cell death 6-interacting protein
— Both
C4B63_10g103 ⚠
Hercynine oxygenase
— Both
C4B63_56g86 ⚠
methylthioadenosine phosphorylase
— OG7
C4B63_2g446 ⚠
Metallocarboxypeptidase 1
— Both
C4B63_63g36 ⚠
prolyl endopeptidase
— Both
C4B63_31g264 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_32g225 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase
— OG7
C4B63_87g24 ⚠
nonspecific lipid-transfer protein
— OG7
C4B63_60g116 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_16g302 ⚠
3-ketoacyl-CoA thiolase
— OG7
C4B63_54g179 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.