C4B63_41g205

alanine aminotransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100524 OG7: OG7_0003566 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g239 ⚠
aldehyde dehydrogenase
— Both
C4B63_81g63 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_50g7 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_80g21 ⚠
Nucleoside diphosphate kinase
— Both
C4B63_8g221 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_32g225 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase
— Both
C4B63_25g288 ⚠
inosine-guanine nucleoside hydrolase
— Both
C4B63_56g86 ⚠
methylthioadenosine phosphorylase
— Both
C4B63_18g164 ⚠
S-adenosylmethionine synthetase
— Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_2g752 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_4g324 ⚠
aconitase
— Both
C4B63_24g246 ⚠
kynureninase
— Both
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_22g59 ⚠
cytidine triphosphate synthase
— Both
C4B63_41g245 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
C4B63_40g121 ⚠
aldehyde dehydrogenase
— OG7
C4B63_41g246 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
C4B63_23g83 ⚠
Aminopeptidase M1
— OG7
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_19g185 ⚠
isocitrate dehydrogenase
— Both
C4B63_170g28 ⚠
adenylosuccinate synthetase
— Both
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_147g45 ⚠
kynureninase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_46g74 ⚠
aminopeptidase
— Both
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_28g60 ⚠
fumarate hydratase
— Both
C4B63_28g106 ⚠
malic enzyme
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_28g107 ⚠
malic enzyme
— Both
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_37g364 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_21g261 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_47g72 ⚠
enolase
— Both
C4B63_23g130 ⚠
Fumarate hydratase class I, cytosolic
— Both
C4B63_2g784 ⚠
glycerol kinase, glycosomal
— Both
C4B63_46g82 ⚠
adenylosuccinate synthetase
— Both
C4B63_4g184 ⚠
citrate synthase
— Both
C4B63_170g15 ⚠
aminopeptidase
— Both
C4B63_8g249 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.