C4B63_37g364

glyceraldehyde 3-phosphate dehydrogenase, cytosolic
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100218 OG7: OG7_0002325 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_295g20 ⚠
tryparedoxin peroxidase
— OG6
C4B63_17g131 ⚠
G5-interacting protein
— OG6
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_295g26 ⚠
glutamate dehydrogenase
— OG6
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— OG6
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— OG6
C4B63_8g546 ⚠
Eukaryotic translation initiation factor 4E t
— OG6
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_186g10 ⚠
G5-interacting protein
— OG6
C4B63_10g404 ⚠
guanine deaminase
— OG6
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— OG6
C4B63_26g206 ⚠
glutaminyl-tRNA synthetase
— OG6
C4B63_18g164 ⚠
S-adenosylmethionine synthetase
— OG6
C4B63_32g236 ⚠
transketolase
— OG6
C4B63_19g183 ⚠
cyclophilin a
— OG6
C4B63_38g47 ⚠
fructose-1,6-bisphosphatase, cytosolic
— OG6
C4B63_227g20 ⚠
pyruvate kinase 2
— OG6
C4B63_248g14 ⚠
glucose-6-phosphate isomerase, glycosomal
— OG6
C4B63_41g194 ⚠
glucose-6-phosphate isomerase, glycosomal
— OG6
C4B63_117g55 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_260g15 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_260g14 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_25g113 ⚠
GMP reductase
— OG6
C4B63_157g32 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_38g299 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_25g288 ⚠
inosine-guanine nucleoside hydrolase
— OG6
C4B63_4g146 ⚠
pyruvate kinase 2
— OG6
C4B63_41g203 ⚠
alanine aminotransferase
— OG6
C4B63_41g205 ⚠
alanine aminotransferase
— OG6
C4B63_6g104 ⚠
mitochondrial RNA binding protein
— OG6
C4B63_48g133 ⚠
poly-zinc-finger protein 2
— OG6
C4B63_48g736c ⚠
universal minicircle sequence binding protein
— OG6
C4B63_48g132 ⚠
universal minicircle sequence binding protein
— OG6
C4B63_26g261 ⚠
glutamate dehydrogenase
— OG6
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_20g170 ⚠
glucosamine-6-phosphate isomerase
— OG6
C4B63_26g253 ⚠
tryparedoxin peroxidase
— OG6
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— OG6
C4B63_220g13 ⚠
cyclophilin
— OG6
C4B63_348g24 ⚠
guanine deaminase
— OG6
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— OG6
C4B63_28g60 ⚠
fumarate hydratase
— OG6
C4B63_220g12 ⚠
peroxidoxin
— OG6
C4B63_149g19 ⚠
peroxidoxin
— OG6
C4B63_26g255 ⚠
tryparedoxin peroxidase
— OG6
C4B63_26g257 ⚠
tryparedoxin peroxidase
— OG6
C4B63_143g20 ⚠
glutamine synthetase
— OG6
C4B63_149g20 ⚠
cyclophilin
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.