C4B63_26g261

glutamate dehydrogenase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_106160 OG7: OG7_0011174 156 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 156 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_22g164 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_304g13 ⚠
nucleosome assembly protein
— Both
C4B63_295g15 ⚠
nucleosome assembly protein-like protein
— Both
C4B63_7g316 ⚠
ruvB-like DNA helicase
— Both
C4B63_263g7 ⚠
ruvB-like DNA helicase
— Both
C4B63_18g141 ⚠
MORN repeat-containing protein 1
— Both
C4B63_1g746 ⚠
mucin TcMUCII
— OG6
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— Both
C4B63_18g312 ⚠
conserved hypothetical protein
— Both
C4B63_17g253 ⚠
Paraflagellar Rod Proteome Component 9
— Both
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— Both
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— Both
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— Both
C4B63_56g104 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— Both
C4B63_31g178 ⚠
Zinc phosphodiesterase ELAC protein 2
— Both
C4B63_31g177 ⚠
ribonuclease Z
— Both
C4B63_17g69 ⚠
phenylalanyl-tRNA synthetase alpha chain
— Both
C4B63_297g14 ⚠
phenylalanyl-tRNA synthetase alpha chain
— Both
C4B63_30g206 ⚠
conserved hypothetical protein
— Both
C4B63_80g21 ⚠
Nucleoside diphosphate kinase
— Both
C4B63_2g784 ⚠
glycerol kinase, glycosomal
— Both
C4B63_163g48 ⚠
conserved hypothetical protein
— Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_30g289 ⚠
WD repeat-containing protein wdr-5.2
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g22 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g257 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g255 ⚠
tryparedoxin peroxidase
— Both
C4B63_149g19 ⚠
peroxidoxin
— Both
C4B63_26g253 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_23g130 ⚠
Fumarate hydratase class I, cytosolic
— Both
C4B63_28g60 ⚠
fumarate hydratase
— Both
C4B63_26g275 ⚠
protein phosphatase 2A regulatory subunit
— Both
C4B63_85g46 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
C4B63_38g169 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_25g192 ⚠
NAA35
— Both
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_61g132 ⚠
WD domain, G-beta repeat
— OG7
C4B63_13g300 ⚠
conserved hypothetical protein
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g65 ⚠
GTP-binding elongation factor Tu family
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_2g88 ⚠
ubiquitin-protein ligase
— OG7
Page 1 of 4
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.