C4B63_12g221

pyruvate phosphate dikinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100727 OG7: OG7_0004964 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_26g253 ⚠
tryparedoxin peroxidase
— Both
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— Both
C4B63_30g161 ⚠
glutamine synthetase
— Both
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_7g347 ⚠
V-type ATPase, A subunit
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_39g357 ⚠
ATP synthase
— Both
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g26 ⚠
glutamate dehydrogenase
— Both
C4B63_47g24 ⚠
Glucose-6-phosphate dehydrogenase
— Both
C4B63_135g22 ⚠
Glucose-6-phosphate dehydrogenase
— Both
C4B63_98g4 ⚠
glucose-6-phosphate 1-dehydrogenase
— Both
C4B63_306g12 ⚠
glucose-6-phosphate 1-dehydrogenase
— Both
C4B63_47g111 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_206g14 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_38g40 ⚠
Reticulocyte-binding protein 2 homolog a
— Both
C4B63_58g70 ⚠
hexokinase
— Both
C4B63_181g13 ⚠
conserved hypothetical protein
— OG7
C4B63_25g968c ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_34g156 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_7g1820c ⚠
acyl-CoA binding protein
— OG7
C4B63_109g69 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_61g73 ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_23g116 ⚠
Importin beta-like SAD2
— OG7
C4B63_19g86 ⚠
CYC2-like cyclin 6
— OG7
C4B63_56g69 ⚠
CYC2-like cyclin
— OG7
C4B63_18g174 ⚠
cyclin
— OG7
C4B63_4g509 ⚠
FKBP-type peptidylprolyl cis-trans isomerase
— OG7
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_13g1005c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_14g27 ⚠
flagellum transition zone component
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.