C4B63_47g111

delta-1-pyrroline-5-carboxylate dehydrogenase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102275 OG7: OG7_0000710 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_70g123 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
C4B63_43g186 ⚠
ATP synthase
— Both
C4B63_59g118 ⚠
phosphoribosylpyrophosphate synthetase
— +1 more Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— Both
C4B63_69g74 ⚠
cytochrome c oxidase subunit V
— Both
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_7g347 ⚠
V-type ATPase, A subunit
— Both
C4B63_54g57 ⚠
vacuolar ATP synthase subunit d
— Both
C4B63_39g357 ⚠
ATP synthase
— Both
C4B63_2g380 ⚠
phosphoribosylpyrophosphate synthetase
— +2 more Both
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— Both
C4B63_123g23 ⚠
cytochrome c oxidase subunit V
— Both
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_248g13 ⚠
ATP synthase subunit
— Both
C4B63_41g1061c ⚠
ATP synthase subunit
— Both
C4B63_58g70 ⚠
hexokinase
— Both
C4B63_128g65 ⚠
prolyl oligopeptidase
— OG7
C4B63_63g37 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_128g64 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_63g36 ⚠
prolyl endopeptidase
— OG7
C4B63_128g66 ⚠
oligopeptidase b(fragment)
— OG7
C4B63_23g212 ⚠
serine/threonine-protein kinase
— OG6
C4B63_2g761 ⚠
Peroxin 19
— Both
C4B63_39g329 ⚠
glycyl-tRNA synthetase
— Both
C4B63_47g53 ⚠
deoxyhypusine synthase
— Both
C4B63_47g52 ⚠
deoxyhypusine synthase
— Both
C4B63_22g292 ⚠
deoxyhypusine synthase
— Both
C4B63_6g564 ⚠
oligopeptidase B-like protein
— Both
C4B63_122g16 ⚠
oligopeptidase b
— Both
C4B63_54g22 ⚠
conserved hypothetical protein
— Both
C4B63_127g35 ⚠
peptidase
— Both
C4B63_18g212 ⚠
valyl-tRNA synthetase
— Both
C4B63_46g91 ⚠
leucyl-tRNA synthetase
— Both
C4B63_18g153 ⚠
T-complex protein 11
— Both
C4B63_54g80 ⚠
conserved hypothetical protein
— Both
C4B63_23g211 ⚠
protein kinase(fragment)
— OG6
C4B63_76g41 ⚠
Probable S-adenosyl-L-methionine-binding prot
— Both
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— +2 more Both
C4B63_295g22 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g257 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g255 ⚠
tryparedoxin peroxidase
— Both
C4B63_149g19 ⚠
peroxidoxin
— Both
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— +1 more Both
C4B63_82g96 ⚠
(H+)-ATPase G subunit
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.