C4B63_58g70

hexokinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100418 OG7: OG7_0002467 25 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 25 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_206g14 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_295g20 ⚠
tryparedoxin peroxidase
— Both
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_2g380 ⚠
phosphoribosylpyrophosphate synthetase
— +5 more Both
C4B63_39g357
ATP synthase
— Both
C4B63_47g111 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_54g57
vacuolar ATP synthase subunit d
— Both
C4B63_295g18 ⚠
tryparedoxin peroxidase
— Both
C4B63_7g347
V-type ATPase, A subunit
— Both
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_295g16 ⚠
tryparedoxin peroxidase
— Both
C4B63_7g133
pyroglutamyl-peptidase I
— Both
C4B63_220g12 ⚠
peroxidoxin
— Both
C4B63_59g118 ⚠
phosphoribosylpyrophosphate synthetase
— +4 more Both
C4B63_26g253 ⚠
tryparedoxin peroxidase
— Both
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— Both
C4B63_82g96 ⚠
(H+)-ATPase G subunit
— Both
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— +3 more Both
C4B63_149g19 ⚠
peroxidoxin
— Both
C4B63_26g255 ⚠
tryparedoxin peroxidase
— Both
C4B63_26g257 ⚠
tryparedoxin peroxidase
— Both
C4B63_295g22 ⚠
tryparedoxin peroxidase
— Both
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— +5 more Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.