C4B63_6g258

Vacuolar proton pump subunit B
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100544 OG7: OG7_0005088 114 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 114 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_39g357 ⚠
ATP synthase
— Both
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_43g186 ⚠
ATP synthase
— Both
C4B63_7g347 ⚠
V-type ATPase, A subunit
— Both
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_91g37 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_56g35 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— Both
C4B63_56g34 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_59g118 ⚠
phosphoribosylpyrophosphate synthetase
— +1 more Both
C4B63_12g330 ⚠
ATP synthase subunit beta, mitochondrial
— Both
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_91g36 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_39g336 ⚠
S-adenosylhomocysteine hydrolase
— Both
C4B63_77g29 ⚠
(H+)-ATPase G subunit
— Both
C4B63_91g38 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_18g171 ⚠
ATP synthase, epsilon chain
— Both
C4B63_56g37 ⚠
ATP synthase F1, alpha subunit
— Both
C4B63_43g126 ⚠
ATP synthase F1 subunit gamma protein
— Both
C4B63_76g41 ⚠
Probable S-adenosyl-L-methionine-binding prot
— Both
C4B63_28g27 ⚠
clathrin coat assembly protein
— Both
C4B63_47g111 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_206g14 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
C4B63_76g32 ⚠
guide RNA associated protein, GAP2
— Both
C4B63_248g13 ⚠
ATP synthase subunit
— Both
C4B63_41g1061c ⚠
ATP synthase subunit
— Both
C4B63_58g70 ⚠
hexokinase
— Both
C4B63_52g51 ⚠
serine/threonine protein kinase
— OG7
C4B63_52g127 ⚠
protein kinase
— OG7
C4B63_14g158 ⚠
serine/threonine kinase
— OG7
C4B63_513g4 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— OG7
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
C4B63_19g264 ⚠
conserved hypothetical protein
— OG7
C4B63_52g128 ⚠
protein kinase
— OG7
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_133g51 ⚠
heat shock protein 70
— OG7
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_61g59 ⚠
Protein kinase domain
— OG7
Page 1 of 3
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.