C4B63_18g32

pseudouridine synthase A-like protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100424 OG7: OG7_0002342 162 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 162 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— Both
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_4g378 ⚠
Zinc finger C2HC domain-containing protein 1C
— OG7
C4B63_392g13 ⚠
conserved hypothetical protein
— OG7
C4B63_80g48 ⚠
conserved hypothetical protein
— OG7
C4B63_10g522 ⚠
FACT complex subunit SPT16
— OG7
C4B63_25g120 ⚠
Protein kinase domain
— OG7
C4B63_54g80 ⚠
conserved hypothetical protein
— OG7
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_4g258 ⚠
prolyl-tRNA synthetase
— OG7
C4B63_392g14 ⚠
conserved hypothetical protein
— OG7
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_21g247 ⚠
conserved hypothetical protein
— OG7
C4B63_52g51 ⚠
serine/threonine protein kinase
— OG7
C4B63_43g175 ⚠
2-oxoisovalerate dehydrogenase alpha subunit
— OG7
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_14g155 ⚠
Leucine-rich repeat-containing protein 74A
— OG7
C4B63_14g144 ⚠
branch point binding protein
— OG7
C4B63_8g540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_52g128 ⚠
protein kinase
— OG7
C4B63_19g264 ⚠
conserved hypothetical protein
— OG7
C4B63_310g13 ⚠
branch point binding protein
— OG7
C4B63_392g11 ⚠
conserved hypothetical protein
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_10g490 ⚠
Hsc70-interacting protein (Hip)
— OG7
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_392g12 ⚠
conserved hypothetical protein
— OG7
C4B63_4g269 ⚠
conserved hypothetical protein
— OG7
C4B63_43g143 ⚠
protein kinase
— OG7
C4B63_14g158 ⚠
serine/threonine kinase
— OG7
C4B63_52g127 ⚠
protein kinase
— OG7
C4B63_227g4 ⚠
Zinc finger protein 474
— OG7
C4B63_70g117 ⚠
Putative tRNA pseudouridine synthase Pus10
— OG7
C4B63_95g23 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_70g126 ⚠
conserved hypothetical protein
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_81g44 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_28g61 ⚠
Methyltransferase-like protein 17, mitochondr
— OG7
C4B63_6g439 ⚠
tRNA pseudouridine synthase
— OG7
C4B63_20g184 ⚠
Pseudouridylate synthase 7 homolog-like prote
— OG7
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_40g27 ⚠
conserved hypothetical protein
— OG7
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
Page 1 of 4
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.