C4B63_70g117

Putative tRNA pseudouridine synthase Pus10
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101927 OG7: OG7_0006809 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_392g12 ⚠
conserved hypothetical protein
— Both
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_30g247
glucosamine-fructose-6-phosphate aminotransfe
— Both
C4B63_4g502 ⚠
ABC transporter
— Both
C4B63_7g358
conserved hypothetical protein
— Both
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— Both
C4B63_70g67
NGG1 interacting factor 3
— Both
C4B63_244g4 ⚠
Nuclear migration protein nudC
— Both
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— Both
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_4g214 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_4g213 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_54g22
conserved hypothetical protein
— Both
C4B63_23g109 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_46g91
leucyl-tRNA synthetase
— Both
C4B63_114g25
conserved hypothetical protein
— Both
C4B63_470g6 ⚠
Protein Simiate
— Both
C4B63_7g278 ⚠
Protein Simiate
— Both
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_22g17
Leucine Rich Repeat
— Both
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_25g214 ⚠
conserved hypothetical protein
— OG7
C4B63_8g211 ⚠
cytochrome b
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_28g210 ⚠
translation initiation factor IF-2
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_28g211 ⚠
translation initiation factor IF-2
— OG7
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_25g215 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_76g56 ⚠
Aminoacyl tRNA synthase complex-interacting m
— OG7
C4B63_55g95 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_40g73 ⚠
glycosyl hydrolase-like protein
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_42g172 ⚠
nuclear movement protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.