C4B63_4g214

cyclophilin type peptidyl-prolyl cis-trans isomerase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_152675 OG7: OG7_0000556 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_197g37 ⚠
JmjC domain-containing protein E
— OG6
C4B63_26g265 ⚠
DNA repair protein Rad9
— OG6
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_244g4 ⚠
Nuclear migration protein nudC
— OG6
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_8g464 ⚠
protein kinase C substrate protein, heavy cha
— OG6
C4B63_23g122 ⚠
serine/threonine protein kinase
— OG6
C4B63_70g117 ⚠
Putative tRNA pseudouridine synthase Pus10
— OG6
C4B63_7g358 ⚠
conserved hypothetical protein
— OG6
C4B63_4g502 ⚠
ABC transporter
— OG6
C4B63_104g78 ⚠
calreticulin
— OG6
C4B63_255g21 ⚠
calreticulin
— OG6
C4B63_10g305 ⚠
conserved hypothetical protein
— OG6
C4B63_95g26 ⚠
conserved hypothetical protein
— OG6
C4B63_30g247 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG6
C4B63_12g208 ⚠
leucine-rich repeat protein (LRRP)
— OG6
C4B63_114g25 ⚠
conserved hypothetical protein
— OG6
C4B63_8g523 ⚠
conserved hypothetical protein
— OG6
C4B63_42g65 ⚠
ubiquitin-protein ligase
— OG6
C4B63_4g182 ⚠
Serine/threonine-protein phosphatase 4 regula
— OG6
C4B63_18g157 ⚠
DNA ligase I
— OG6
C4B63_18g138 ⚠
UV excision repair RAD23-like protein
— OG6
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
C4B63_49g81 ⚠
translation initiation factor IF-2
— OG6
C4B63_227g2 ⚠
glucan 1,3-alpha-glucosidase
— OG6
C4B63_4g375 ⚠
glucan 1,3-alpha-glucosidase
— OG6
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_28g91 ⚠
Kinesin-13 3
— OG6
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— OG6
C4B63_23g248 ⚠
inorganic pyrophosphatase
— OG6
C4B63_57g113 ⚠
Flagellar Member 2
— OG6
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— OG6
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— OG6
C4B63_56g85 ⚠
conserved hypothetical protein
— OG6
C4B63_56g84 ⚠
conserved hypothetical protein
— OG6
C4B63_34g118 ⚠
conserved hypothetical protein
— OG6
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG6
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG6
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_8g191 ⚠
JmjC domain-containing protein E
— OG6
C4B63_23g207 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG6
C4B63_81g44 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG6
C4B63_54g28 ⚠
conserved hypothetical protein
— OG6
C4B63_184g38 ⚠
TPR-repeat protein
— OG6
C4B63_13g167 ⚠
stress-inducible protein STI1-like
— OG6
C4B63_4g176 ⚠
Zn-finger in Ran binding protein and others/F
— OG6
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.