C4B63_4g176

Zn-finger in Ran binding protein and others/FYVE zinc-finger
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139898 OG7: OG7_0001169 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g208
leucine-rich repeat protein (LRRP)
— OG6
C4B63_30g247
glucosamine-fructose-6-phosphate aminotransfe
— OG6
C4B63_25g260 ⚠
TBC1 domain family member 5
— OG6
C4B63_31g99
WD repeat-containing protein 17
— OG6
C4B63_12g212 ⚠
conserved hypothetical protein
— OG6
C4B63_12g211 ⚠
conserved hypothetical protein
— OG6
C4B63_8g191 ⚠
JmjC domain-containing protein E
— OG6
C4B63_197g37 ⚠
JmjC domain-containing protein E
— OG6
C4B63_42g65
ubiquitin-protein ligase
— OG6
C4B63_8g523
conserved hypothetical protein
— OG6
C4B63_22g77
conserved hypothetical protein
— OG6
C4B63_300g17 ⚠
E3 ubiquitin-protein ligase MGRN1
— OG6
C4B63_34g319 ⚠
E3 ubiquitin-protein ligase MGRN1
— OG6
C4B63_95g26
conserved hypothetical protein
— OG6
C4B63_10g305
conserved hypothetical protein
— OG6
C4B63_44g234
CRAL/TRIO domain containing protein
— OG6
C4B63_117g55 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_102g53
conserved hypothetical protein
— OG6
C4B63_282g21 ⚠
conserved hypothetical protein
— OG6
C4B63_26g265
DNA repair protein Rad9
— OG6
C4B63_57g113
Flagellar Member 2
— OG6
C4B63_6g521
DIS3-like exonuclease
— OG6
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG6
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG6
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— OG6
C4B63_4g213 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_4g214 ⚠
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
C4B63_2g768
RNA-binding protein
— OG6
C4B63_136g37 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG6
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— OG6
C4B63_136g36 ⚠
Alanyl-tRNA editing protein Aarsd1
— OG6
C4B63_26g317 ⚠
Alanyl-tRNA editing protein Aarsd1-B
— OG6
C4B63_21g251
conserved hypothetical protein
— OG6
C4B63_232g3 ⚠
TBC1 domain family member 5
— OG6
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— OG6
C4B63_4g182
Serine/threonine-protein phosphatase 4 regula
— OG6
C4B63_5g416 ⚠
conserved hypothetical protein
— OG6
C4B63_48g166 ⚠
serine/cysteine trypsin-like peptidase
— OG6
C4B63_4g234 ⚠
5-oxoprolinase
— OG6
C4B63_260g14 ⚠
inosine-5'-monophosphate dehydrogenase
— OG6
C4B63_314g10 ⚠
5'-AMP-activated protein kinase subunit beta
— OG6
C4B63_4g258
prolyl-tRNA synthetase
— OG6
C4B63_2g5
casein kinase II
— OG6
C4B63_42g187
conserved hypothetical protein
— OG6
C4B63_23g275
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_1g73 ⚠
conserved hypothetical protein
— OG6
C4B63_18g50
microtubule associated protein xmap215
— OG6
C4B63_23g122
serine/threonine protein kinase
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.