C4B63_18g50

microtubule associated protein xmap215
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101795 OG7: OG7_0005125 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_13g295 ⚠
pumilio/PUF RNA binding protein 6
— OG7
C4B63_12g211 ⚠
conserved hypothetical protein
— Both
C4B63_12g212 ⚠
conserved hypothetical protein
— Both
C4B63_31g99
WD repeat-containing protein 17
— Both
C4B63_142g11 ⚠
Protein shuttle craft
— Both
C4B63_12g208
leucine-rich repeat protein (LRRP)
— Both
C4B63_10g293
Phosphatidylinositol 4-phosphate 5-kinase 6
— OG6
C4B63_6g400 ⚠
conserved hypothetical protein
— Both
C4B63_282g21 ⚠
conserved hypothetical protein
— Both
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_4g235 ⚠
5-oxoprolinase
— Both
C4B63_4g234 ⚠
5-oxoprolinase
— Both
C4B63_16g140 ⚠
Paladin
— Both
C4B63_259g15 ⚠
Paladin
— Both
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_7g388 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_24g301
phosphatidylinositol-4-phosphate 5-kinase
— OG7
C4B63_413g14 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_22g175 ⚠
pumilio/PUF RNA binding protein 9
— OG7
C4B63_6g592 ⚠
pumilio/PUF RNA binding protein 5
— OG7
C4B63_204g19 ⚠
pumilio/PUF RNA binding protein 6
— OG7
C4B63_41g148 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_439g12 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_13g170 ⚠
pumilio/PUF RNA binding protein 1
— OG7
C4B63_97g23 ⚠
pumilio/PUF RNA binding protein 2
— OG7
C4B63_43g137 ⚠
pumilio/PUF RNA binding protein 3
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_44g125 ⚠
conserved hypothetical protein
— OG7
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_44g232 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_359g23 ⚠
CRAL/TRIO domain containing protein
— OG7
C4B63_249g17 ⚠
conserved hypothetical protein
— OG7
C4B63_359g17 ⚠
conserved hypothetical protein
— OG7
C4B63_249g12 ⚠
conserved hypothetical protein
— OG7
C4B63_92g114 ⚠
conserved hypothetical protein
— OG7
C4B63_359g9 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_18g1175c ⚠
conserved hypothetical protein
— OG7
C4B63_2g815 ⚠
conserved hypothetical protein
— OG7
C4B63_488g7 ⚠
conserved hypothetical protein
— OG7
C4B63_92g124 ⚠
conserved hypothetical protein
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.