C4B63_12g208

leucine-rich repeat protein (LRRP)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147133 OG7: OG7_0037776 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_22g23 ⚠
ARM-like helical domain-containing protein
— Both
C4B63_22g22 ⚠
ARM-like helical domain-containing protein
— Both
C4B63_42g65
ubiquitin-protein ligase
— OG6
C4B63_4g176
Zn-finger in Ran binding protein and others/F
— OG6
C4B63_8g190 ⚠
conserved hypothetical protein
— OG7
C4B63_84g82
DNA mismatch repair protein MSH2
— Both
C4B63_260g15 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_8g54
conserved hypothetical protein
— Both
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— Both
C4B63_2g768
RNA-binding protein
— Both
C4B63_282g21 ⚠
conserved hypothetical protein
— Both
C4B63_102g53
conserved hypothetical protein
— Both
C4B63_82g92 ⚠
conserved hypothetical protein
— Both
C4B63_4g269
conserved hypothetical protein
— Both
C4B63_117g55 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
C4B63_44g234 ⚠
CRAL/TRIO domain containing protein
— Both
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_42g42
co-chaperone GrpE
— OG7
C4B63_359g9 ⚠
conserved hypothetical protein
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_2g815 ⚠
conserved hypothetical protein
— OG7
C4B63_488g7 ⚠
conserved hypothetical protein
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_92g124 ⚠
conserved hypothetical protein
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_92g114 ⚠
conserved hypothetical protein
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g817 ⚠
conserved hypothetical protein
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_42g593c ⚠
small nuclear ribonucleoprotein Sm-E
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_7g388 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g816 ⚠
conserved hypothetical protein
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_249g12 ⚠
conserved hypothetical protein
— OG7
C4B63_7g382 ⚠
ubiquitin-protein ligase
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_13g231 ⚠
serine/threonine protein kinase
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.