C4B63_61g81

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_142131 OG7: OG7_0001167 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
C4B63_513g4 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_37g370 ⚠
conserved hypothetical protein
— OG7
C4B63_22g109 ⚠
MORN repeat-containing protein
— OG7
C4B63_84g82 ⚠
DNA mismatch repair protein MSH2
— OG7
C4B63_8g54 ⚠
conserved hypothetical protein
— OG7
C4B63_54g82 ⚠
conserved hypothetical protein
— OG7
C4B63_267g91c ⚠
DNA-directed RNA polymerase I subunit RPB10
— OG7
C4B63_282g21 ⚠
conserved hypothetical protein
— OG7
C4B63_2g768 ⚠
RNA-binding protein
— OG7
C4B63_330g12 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_6g268 ⚠
conserved hypothetical protein
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG7
C4B63_11g283c ⚠
U6 snRNA-associated Sm-like protein LSm8
— OG7
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— OG7
C4B63_6g517 ⚠
geranylgeranyl transferase type II beta subun
— OG7
C4B63_2g1123c ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
C4B63_18g263 ⚠
SPA/DENN domain containing protein
— OG7
C4B63_10g167 ⚠
conserved hypothetical protein
— OG7
C4B63_4g269 ⚠
conserved hypothetical protein
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_41g73 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g218 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_248g25 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_51g105 ⚠
conserved hypothetical protein
— OG7
C4B63_70g58 ⚠
protein kinase
— OG7
C4B63_7g98 ⚠
Eukaryotic translation initiation factor 2-al
— OG7
C4B63_1g23 ⚠
conserved hypothetical protein
— OG7
C4B63_76g32 ⚠
guide RNA associated protein, GAP2
— OG7
C4B63_1g24 ⚠
conserved hypothetical protein
— OG7
C4B63_31g76 ⚠
ubiquitin-activating enzyme
— OG7
C4B63_85g75 ⚠
ubiquitin activating enzyme
— OG7
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG7
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_233g32 ⚠
ubiquitin hydrolase
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_12g212 ⚠
conserved hypothetical protein
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_30g245 ⚠
conserved hypothetical protein
— OG7
C4B63_31g99 ⚠
WD repeat-containing protein 17
— OG7
C4B63_22g82 ⚠
conserved hypothetical protein
— OG7
C4B63_12g211 ⚠
conserved hypothetical protein
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.