C4B63_26g232

ubiquitin hydrolase(fragment)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_145141 OG7: OG7_0002166 291 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 291 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_206g11 ⚠
ABC transporter
— Both
C4B63_47g107 ⚠
ABC transporter
— Both
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_16g331 ⚠
ubiquitin-activating enzyme E1
— OG7
C4B63_153g42 ⚠
cAMP-specific phosphodiesterase
— Both
C4B63_72g80 ⚠
cAMP-specific phosphodiesterase
— Both
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_17g55 ⚠
cyclin 9
— OG7
C4B63_243g12 ⚠
Vacuolar protein sorting-associated protein V
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_61g104 ⚠
conserved hypothetical protein
— OG7
C4B63_2g46 ⚠
conserved hypothetical protein
— OG7
C4B63_2g761 ⚠
Peroxin 19
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_17g98 ⚠
E3 ubiquitin-protein ligase UPL3
— OG7
C4B63_24g227 ⚠
conserved hypothetical protein
— OG7
C4B63_330g11 ⚠
conserved hypothetical protein
— OG7
C4B63_2g47 ⚠
conserved hypothetical protein
— OG7
C4B63_28g87 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_79g39 ⚠
conserved hypothetical protein
— OG7
C4B63_161g30 ⚠
conserved hypothetical protein
— OG7
C4B63_54g62 ⚠
proteasome activator protein pa26
— OG7
C4B63_4g1058c ⚠
sporangia induced deflagellation-inducible pr
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_97g26 ⚠
conserved hypothetical protein
— OG7
C4B63_9g383 ⚠
conserved hypothetical protein
— OG7
C4B63_24g228 ⚠
conserved hypothetical protein
— OG7
C4B63_42g96 ⚠
ubiquitin hydrolase
— OG7
C4B63_58g121 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_14g40 ⚠
conserved hypothetical protein
— OG7
C4B63_18g212 ⚠
valyl-tRNA synthetase
— OG7
C4B63_19g113 ⚠
Translation machinery-associated protein 22
— OG7
C4B63_95g32 ⚠
conserved hypothetical protein
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_20g152 ⚠
Uncharacterized GTP-binding protein C428.15
— OG7
C4B63_12g179 ⚠
anion-transporting ATPase-like
— OG7
C4B63_113g49 ⚠
metallo-peptidase, Clan MC, Family M14
— OG7
C4B63_212g12 ⚠
anion-transporting ATPase-like
— OG7
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— OG7
C4B63_9g201 ⚠
GTP-binding protein
— OG7
C4B63_184g8 ⚠
GTP-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.