C4B63_91g35

GTPase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101829 OG7: OG7_0001608 259 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 259 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_19g86 ⚠
CYC2-like cyclin 6
— OG7
C4B63_7g241 ⚠
ribosomal protein L3
— OG7
C4B63_7g244 ⚠
ribosomal protein L3
— OG7
C4B63_7g240 ⚠
ribosomal protein L3
— OG7
C4B63_7g243 ⚠
ribosomal protein L3
— OG7
C4B63_7g242 ⚠
ribosomal protein L3
— OG7
C4B63_7g245 ⚠
ribosomal protein L3
— OG7
C4B63_233g19 ⚠
ribosomal protein L15
— OG7
C4B63_75g49 ⚠
ribosomal protein L15
— OG7
C4B63_18g176 ⚠
ribosomal protein L15
— OG7
C4B63_57g103 ⚠
conserved hypothetical protein
— OG7
C4B63_243g12 ⚠
Vacuolar protein sorting-associated protein V
— OG7
C4B63_56g75 ⚠
Vacuolar protein sorting-associated protein V
— OG7
C4B63_10g137 ⚠
conserved hypothetical protein
— OG7
C4B63_2g564 ⚠
mRNA export factor MEX67
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_127g35 ⚠
peptidase
— OG7
C4B63_294g18 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_76g60 ⚠
N-acetyltransferase
— OG7
C4B63_8g522 ⚠
conserved hypothetical protein
— OG7
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
C4B63_21g280 ⚠
ribonuclease mar1
— OG7
C4B63_17g63 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— OG7
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— OG7
C4B63_31g273 ⚠
XRN 5'-3' exonuclease N-terminus
— OG7
C4B63_49g130 ⚠
Putative hydrolase C777.06c
— OG7
C4B63_42g192 ⚠
N-alpha-acetyltransferase 25, NatB auxiliary
— OG7
C4B63_61g73 ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_22g79 ⚠
Tubulin/FtsZ family
— OG7
C4B63_134g72 ⚠
XRN 5'-3' exonuclease N-terminus
— OG7
C4B63_49g131 ⚠
conserved hypothetical protein
— OG7
C4B63_134g73 ⚠
conserved hypothetical protein
— OG7
C4B63_18g174 ⚠
cyclin
— OG7
C4B63_51g110 ⚠
Importin beta-like SAD2
— OG7
C4B63_35g155 ⚠
aspartate carbamoyltransferase
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_93g64 ⚠
amidohydrolase
— OG7
C4B63_4g509 ⚠
FKBP-type peptidylprolyl cis-trans isomerase
— OG7
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_13g1005c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_18g219 ⚠
tRNA methyltransferase 10 homolog A
— OG7
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_293g2 ⚠
p22 protein precursor (Mitochondrial glycopro
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_60g125 ⚠
XRN 5'-3' exonuclease N-terminus
— OG7
C4B63_233g31 ⚠
ubiquitin hydrolase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.