C4B63_93g64

amidohydrolase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101553 OG7: OG7_0005942 196 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 196 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— +7 more Both
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— +9 more Both
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— +9 more Both
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— +9 more Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_30g129 ⚠
rrp44p homologue
— +1 more Both
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_157g28 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_83g79 ⚠
RNA pseudouridylate synthase
— OG7
C4B63_44g117 ⚠
conserved hypothetical protein
— OG7
C4B63_49g325c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_52g161 ⚠
tyrosyl-tRNA synthetase
— OG7
C4B63_7g316 ⚠
ruvB-like DNA helicase
— OG7
C4B63_263g7 ⚠
ruvB-like DNA helicase
— OG7
C4B63_61g73 ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_109g69 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_7g1820c ⚠
acyl-CoA binding protein
— OG7
C4B63_47g34 ⚠
mitochondrial malate dehydrogenase
— Both
C4B63_18g219 ⚠
tRNA methyltransferase 10 homolog A
— Both
C4B63_6g384 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— Both
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_8g191 ⚠
JmjC domain-containing protein E
— Both
C4B63_32g257 ⚠
Cyclin-U3-1
— Both
C4B63_8g58 ⚠
Dynein assembly factor 1, axonemal homolog
— Both
C4B63_8g522 ⚠
conserved hypothetical protein
— Both
C4B63_2g564 ⚠
mRNA export factor MEX67
— Both
C4B63_2g176 ⚠
elongation factor 1-alpha
— OG6
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_25g968c ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_181g13 ⚠
conserved hypothetical protein
— OG7
C4B63_23g116 ⚠
Importin beta-like SAD2
— OG7
C4B63_22g77 ⚠
conserved hypothetical protein
— Both
C4B63_42g42 ⚠
co-chaperone GrpE
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_40g52 ⚠
conserved hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.