C4B63_40g52

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147153 OG7: OG7_0043154 102 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 102 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— +2 more Both
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— +2 more Both
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— +2 more Both
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— +2 more Both
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_70g68 ⚠
cell cycle sequence binding phosphoprotein (R
— OG6
C4B63_111g26 ⚠
cell cycle sequence binding phosphoprotein (R
— OG6
C4B63_63g4 ⚠
PSP1 C-terminal conserved region
— OG6
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_286g15 ⚠
PSP1 C-terminal conserved region
— OG6
C4B63_9g247
small nuclear ribonucleoprotein protein
— Both
C4B63_12g28
RNA-binding protein
— OG6
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_52g157
serine hydroxymethyltransferase
— Both
C4B63_25g192
NAA35
— Both
C4B63_40g126
TOM1-like protein 9
— Both
C4B63_93g65 ⚠
amidohydrolase
— Both
C4B63_25g329 ⚠
Nuclear migration protein nudC
— Both
C4B63_93g64 ⚠
amidohydrolase
— Both
C4B63_244g4 ⚠
Nuclear migration protein nudC
— Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— Both
C4B63_42g42
co-chaperone GrpE
— Both
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_13g1005c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_4g509 ⚠
FKBP-type peptidylprolyl cis-trans isomerase
— OG7
C4B63_49g325c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_4g508 ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_171g30 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_157g28 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_42g172 ⚠
nuclear movement protein
— OG7
C4B63_8g48 ⚠
dynein arm light chain
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_102g78 ⚠
dynein arm light chain
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_19g113
Translation machinery-associated protein 22
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_173g6 ⚠
Soluble NSF attachment protein, SNAP (parafla
— Both
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_52g161 ⚠
tyrosyl-tRNA synthetase
— OG7
C4B63_25g215 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.