C4B63_204g23

Axonemal inner arm dynein light chain
Trypanosoma cruzi Dm28c 2018 OG6: OG6_158294 OG7: OG7_0006990 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_42g85 ⚠
conserved hypothetical protein
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_4g331 ⚠
tubulin-specific chaperone
— OG7
C4B63_4g506 ⚠
Microtubule Associated kinase (CAP-Gly domain
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_40g52 ⚠
conserved hypothetical protein
— OG7
C4B63_12g196 ⚠
conserved hypothetical protein
— OG7
C4B63_4g531 ⚠
Cleavage stimulation factor subunit 1
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_2g359 ⚠
DDB1- and CUL4-associated factor 1
— OG7
C4B63_72g79 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_43g154 ⚠
TRAF3-interacting protein 1
— OG7
C4B63_13g257 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_2g13 ⚠
Centrosomal protein of 131 kDa
— OG7
C4B63_26g245 ⚠
inositol/phosphatidylinositol phosphatase
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_42g254 ⚠
conserved hypothetical protein
— OG7
C4B63_2g203 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_24g195 ⚠
microtubule-associated protein
— OG7
C4B63_24g194 ⚠
microtubule-associated protein
— OG7
C4B63_153g40 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_102g78 ⚠
dynein arm light chain
— OG7
C4B63_2g826 ⚠
conserved hypothetical protein
— OG7
C4B63_2g54 ⚠
conserved hypothetical protein
— OG7
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_48g116 ⚠
5'-3' exoribonuclease D
— OG7
C4B63_233g5 ⚠
Proteasomal ubiquitin receptor ADRM1
— OG7
C4B63_79g36 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_89g51 ⚠
FYVE zinc-finger containing protein
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_11g50 ⚠
General negative regulator of transcription s
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.