C4B63_42g254

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_134892 OG7: OG7_0037731 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_56g104 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— Both
C4B63_80g9 ⚠
conserved hypothetical protein
— Both
C4B63_4g242 ⚠
protein kinase A catalytic subunit 3
— OG6
C4B63_4g103
intraflagellar transport protein 140
— Both
C4B63_17g45
kinesin
— OG6
C4B63_18g71 ⚠
cyclosome subunit
— Both
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_63g98
ubiquitin-protein ligase
— OG6
C4B63_17g276 ⚠
TRAF3-interacting protein 1
— Both
C4B63_48g156 ⚠
conserved hypothetical protein
— OG6
C4B63_48g155 ⚠
conserved hypothetical protein
— OG6
C4B63_13g334
conserved hypothetical protein
— Both
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— Both
C4B63_13g243
intraflagellar transport protein 122B(fragmen
— Both
C4B63_42g174
conserved hypothetical protein
— Both
C4B63_18g72 ⚠
cyclosome subunit
— Both
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_52g40
immunodominant antigen
— Both
C4B63_24g195 ⚠
microtubule-associated protein
— Both
C4B63_24g194 ⚠
microtubule-associated protein
— Both
C4B63_24g196 ⚠
microtubule-associated protein
— Both
C4B63_30g273 ⚠
conserved hypothetical protein
— Both
C4B63_163g31 ⚠
conserved hypothetical protein
— Both
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— Both
C4B63_89g42 ⚠
translation initiation factor EIF-2b alpha su
— Both
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g21 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g24 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_28g122 ⚠
conserved hypothetical protein
— Both
C4B63_28g123 ⚠
conserved hypothetical protein
— Both
C4B63_1g57
AAA ATPase
— Both
C4B63_76g43
proteasome regulatory ATPase subunit 1
— OG6
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_281g8 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_21g61 ⚠
guanine nucleotide exchange factor subunit GC
— OG7
C4B63_19g15 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_22g288
Midasin
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_10g132
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.