C4B63_17g276

TRAF3-interacting protein 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147598 OG7: OG7_0008266 130 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 130 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g294 ⚠
Putative intraflagellar transport protein A1
— OG7
C4B63_1g57 ⚠
AAA ATPase
— Both
C4B63_76g43
proteasome regulatory ATPase subunit 1
— OG6
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_281g8 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_21g61 ⚠
guanine nucleotide exchange factor subunit GC
— OG7
C4B63_19g15 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g218 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_137g42 ⚠
gamma-tubulin complex component 3
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_46g32 ⚠
E3 ubiquitin-protein ligase HERC2
— OG7
C4B63_6g318 ⚠
gamma-tubulin complex component 3
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_47g42 ⚠
intraflagellar transport protein 81
— OG7
C4B63_4g331 ⚠
tubulin-specific chaperone
— OG7
C4B63_281g16 ⚠
intraflagellar transport protein 88
— OG7
C4B63_49g64 ⚠
Intraflagellar transport protein 74 homolog
— OG7
C4B63_4g431 ⚠
intraflagellar transport protein 52
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_40g148 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_323g7 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_156g7 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_40g188 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_7g62 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_102g74 ⚠
intraflagellar transport protein 172
— OG7
C4B63_168g27 ⚠
intraflagellar transport protein 172
— OG7
C4B63_168g26 ⚠
intraflagellar transport protein 172
— OG7
C4B63_19g23 ⚠
intraflagellar transport protein 88
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.