C4B63_49g64

Intraflagellar transport protein 74 homolog

Trypanosoma cruzi Dm28c 2018 OG6: OG6_104280 OG7: OG7_0009310 36 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 36 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_10g506 Tetratricopeptide repeat protein 30A	—	OG6 LdBPK_221220.1 ↔ LdBPK_290160.1 OG6 Tb927.3.5490 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_290160.1 OG7 Tb927.3.5490 ↔ Tb927.7.3370	Both
C4B63_10g515 intraflagellar transport protein 27	—	OG6 LdBPK_221220.1 ↔ LdBPK_290090.1 OG6 Tb927.3.5550 ↔ Tb927.7.3370	OG6
C4B63_18g51 Intraflagellar transport protein 46 homolog	—	OG6 LdBPK_221220.1 ↔ LdBPK_301770.1 OG6 Tb927.6.3100 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_301770.1 OG7 Tb927.6.3100 ↔ Tb927.7.3370	Both
C4B63_20g161 Intraflagellar transport protein 22	—	OG6 LdBPK_221220.1 ↔ LdBPK_323410.1 OG6 Tb927.11.16830 ↔ Tb927.7.3370 OG7 Tb927.11.16830 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_323410.1	Both
C4B63_12g294 ⚠ Putative intraflagellar transport protein A1	—	OG6 LdBPK_221220.1 ↔ LdBPK_251470.1 OG6 Tb927.3.1110 ↔ Tb927.7.3370 OG7 Tb927.3.1110 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_251470.1	Both
C4B63_168g27 ⚠ intraflagellar transport protein 172	—	OG6 LdBPK_211220.1 ↔ LdBPK_221220.1 OG6 Tb927.10.1170 ↔ Tb927.7.3370 OG7 LdBPK_211220.1 ↔ LdBPK_221220.1 OG7 Tb927.10.1170 ↔ Tb927.7.3370	Both
C4B63_102g74 ⚠ intraflagellar transport protein 172	—	OG6 LdBPK_211220.1 ↔ LdBPK_221220.1 OG6 Tb927.10.1170 ↔ Tb927.7.3370 OG7 LdBPK_211220.1 ↔ LdBPK_221220.1 OG7 Tb927.10.1170 ↔ Tb927.7.3370	Both
C4B63_281g16 ⚠ intraflagellar transport protein 88	—	OG6 LdBPK_221220.1 ↔ LdBPK_271010.1 OG6 Tb927.11.1740 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_271010.1 OG7 Tb927.11.1740 ↔ Tb927.7.3370	Both
C4B63_47g42 intraflagellar transport protein 81	—	OG6 LdBPK_221220.1 ↔ LdBPK_340250.1 OG6 Tb927.10.2640 ↔ Tb927.7.3370 OG7 Tb927.10.2640 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_340250.1	Both
C4B63_120g74 ⚠ Putative intraflagellar transport protein A1(	—	OG6 LdBPK_221220.1 ↔ LdBPK_251470.1 OG6 Tb927.3.1110 ↔ Tb927.7.3370 OG7 Tb927.3.1110 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_251470.1	Both
C4B63_19g23 ⚠ intraflagellar transport protein 88	—	OG6 LdBPK_221220.1 ↔ LdBPK_271010.1 OG6 Tb927.11.1740 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_271010.1 OG7 Tb927.11.1740 ↔ Tb927.7.3370	Both
C4B63_120g75 ⚠ Putative intraflagellar transport protein A1(	—	OG6 LdBPK_221220.1 ↔ LdBPK_251470.1 OG6 Tb927.3.1110 ↔ Tb927.7.3370 OG7 Tb927.3.1110 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_251470.1	Both
C4B63_168g26 ⚠ intraflagellar transport protein 172	—	OG6 LdBPK_211220.1 ↔ LdBPK_221220.1 OG6 Tb927.10.1170 ↔ Tb927.7.3370 OG7 LdBPK_211220.1 ↔ LdBPK_221220.1 OG7 Tb927.10.1170 ↔ Tb927.7.3370	Both
C4B63_84g18 intraflagellar transport protein 57/55	—	OG6 LdBPK_221220.1 ↔ LdBPK_330670.1 OG6 Tb927.10.11310 ↔ Tb927.7.3370 OG7 Tb927.10.11310 ↔ Tb927.7.3370 OG7 LdBPK_221220.1 ↔ LdBPK_330670.1	Both
C4B63_4g431 intraflagellar transport protein 52	—	OG6 Tb927.10.14980 ↔ Tb927.7.3370 OG6 LdBPK_190320.1 ↔ LdBPK_221220.1 OG7 LdBPK_190320.1 ↔ LdBPK_221220.1 OG7 Tb927.10.14980 ↔ Tb927.7.3370	Both
C4B63_1g68 Intraflagellar transport protein 25	—	OG6 LdBPK_091200.1 ↔ LdBPK_221220.1 OG7 LdBPK_091200.1 ↔ LdBPK_221220.1	Both
C4B63_111g29 conserved hypothetical protein	—	OG6 Tb927.5.780 ↔ Tb927.7.3370 OG7 Tb927.5.780 ↔ Tb927.7.3370	Both
C4B63_17g276 ⚠ TRAF3-interacting protein 1	—	OG7 Tb927.10.450 ↔ Tb927.7.3370	OG7
C4B63_23g228 ⚠ START domain-containing protein 10	—	OG6 Tb927.3.3030 ↔ Tb927.7.3370 OG7 Tb927.3.3030 ↔ Tb927.7.3370	Both
C4B63_43g154 ⚠ TRAF3-interacting protein 1	—	OG6 Tb927.10.450 ↔ Tb927.7.3370 OG7 Tb927.10.450 ↔ Tb927.7.3370	Both
C4B63_12g206 ⚠ START domain-containing protein 10	—	OG7 Tb927.3.3030 ↔ Tb927.7.3370	OG7
C4B63_40g131 ⚠ conserved hypothetical protein	—	OG7 LdBPK_221220.1 ↔ LdBPK_365330.1	OG7
C4B63_8g496 conserved hypothetical protein	—	OG7 LdBPK_221220.1 ↔ LdBPK_260700.1	OG7
C4B63_207g7 ⚠ conserved hypothetical protein	—	OG6 LdBPK_190020.1 ↔ LdBPK_221220.1 OG7 LdBPK_190020.1 ↔ LdBPK_221220.1	Both
C4B63_4g432 intraflagellar transport protein 80	—	OG6 Tb927.10.14990 ↔ Tb927.7.3370 OG7 Tb927.10.14990 ↔ Tb927.7.3370	Both
C4B63_319g1 ⚠ conserved hypothetical protein	—	OG6 LdBPK_221220.1 ↔ LdBPK_365330.1 OG7 LdBPK_221220.1 ↔ LdBPK_365330.1	Both
C4B63_40g189 ⚠ 40S ribosomal protein SA	—	OG6 LdBPK_221220.1 ↔ LdBPK_365240.1 OG7 LdBPK_221220.1 ↔ LdBPK_365240.1	Both
C4B63_40g132 ⚠ conserved hypothetical protein	—	OG6 LdBPK_221220.1 ↔ LdBPK_365330.1 OG7 LdBPK_221220.1 ↔ LdBPK_365330.1	Both
C4B63_2g444 RRP12	—	OG6 LdBPK_221220.1 ↔ LdBPK_332660.1 OG7 LdBPK_221220.1 ↔ LdBPK_332660.1	Both
C4B63_40g149 ⚠ 40S ribosomal protein SA	—	OG6 LdBPK_221220.1 ↔ LdBPK_365240.1 OG7 LdBPK_221220.1 ↔ LdBPK_365240.1	Both
C4B63_319g2 ⚠ conserved hypothetical protein	—	OG6 LdBPK_221220.1 ↔ LdBPK_365330.1 OG7 LdBPK_221220.1 ↔ LdBPK_365330.1	Both
C4B63_23g230 Putative intraflagellar transport protein C3	—	OG6 LdBPK_221220.1 ↔ LdBPK_292870.1 OG7 LdBPK_221220.1 ↔ LdBPK_292870.1	Both
C4B63_6g487 conserved hypothetical protein	—	OG6 Tb927.11.8030 ↔ Tb927.7.3370 OG7 Tb927.11.8030 ↔ Tb927.7.3370	Both
C4B63_40g129 ⚠ 40S ribosomal protein SA	—	OG6 LdBPK_221220.1 ↔ LdBPK_365240.1 OG7 LdBPK_221220.1 ↔ LdBPK_365240.1	Both
C4B63_18g184c intraflagellar transport (IFT) protein	—	OG6 Tb927.6.3290 ↔ Tb927.7.3370 OG7 Tb927.6.3290 ↔ Tb927.7.3370	Both
C4B63_4g77 ⚠ conserved hypothetical protein	—	OG6 LdBPK_190020.1 ↔ LdBPK_221220.1 OG7 LdBPK_190020.1 ↔ LdBPK_221220.1	Both