C4B63_31g46

structural maintenance of chromosome 3 protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101525 OG7: OG7_0001761 255 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 255 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_16g101 ⚠
conserved hypothetical protein
— OG7
C4B63_16g102 ⚠
conserved hypothetical protein
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_14g174 ⚠
gamma-tubulin complex component 2
— OG7
C4B63_30g181 ⚠
rRNA methyltransferase 1, mitochondrial
— OG7
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_220g9 ⚠
conserved hypothetical protein
— OG7
C4B63_81g52 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_2g63 ⚠
conserved hypothetical protein
— OG7
C4B63_43g154 ⚠
TRAF3-interacting protein 1
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_2g62 ⚠
conserved hypothetical protein
— OG7
C4B63_279g6 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_59g118 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_89g51 ⚠
FYVE zinc-finger containing protein
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— +2 more OG7
C4B63_61g104 ⚠
conserved hypothetical protein
— OG7
C4B63_4g331 ⚠
tubulin-specific chaperone
— OG7
C4B63_4g506 ⚠
Microtubule Associated kinase (CAP-Gly domain
— OG7
C4B63_12g196 ⚠
conserved hypothetical protein
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_7g62 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_40g188 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_156g7 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_323g7 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_40g148 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_34g113 ⚠
Cilia- and flagella-associated protein 58
— OG7
C4B63_23g265 ⚠
conserved hypothetical protein
— OG7
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.