C4B63_127g31

Flagellum attachment zone protein 14
Trypanosoma cruzi Dm28c 2018 OG6: OG6_223577 OG7: OG7_0044583 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g132 ⚠
conserved hypothetical protein
— OG7
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_13g243 ⚠
intraflagellar transport protein 122B(fragmen
— OG7
C4B63_46g32 ⚠
E3 ubiquitin-protein ligase HERC2
— OG7
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG7
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_4g111 ⚠
conserved hypothetical protein
— OG7
C4B63_80g9 ⚠
conserved hypothetical protein
— OG7
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— OG7
C4B63_18g72 ⚠
cyclosome subunit
— OG7
C4B63_18g71 ⚠
cyclosome subunit
— OG7
C4B63_34g309 ⚠
proteasome regulatory non-ATPase subunit 6
— OG7
C4B63_28g122 ⚠
conserved hypothetical protein
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_42g168 ⚠
CDC16
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_149g16 ⚠
conserved hypothetical protein
— OG7
C4B63_220g9 ⚠
conserved hypothetical protein
— OG7
C4B63_61g104 ⚠
conserved hypothetical protein
— OG7
C4B63_351g1 ⚠
conserved hypothetical protein
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_4g513 ⚠
Target of rapamycin complex subunit LST8
— OG7
C4B63_32g247 ⚠
conserved hypothetical protein
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_42g254 ⚠
conserved hypothetical protein
— OG7
C4B63_42g174 ⚠
conserved hypothetical protein
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG7
C4B63_22g166 ⚠
Regulatory-associated protein of mTOR
— OG7
C4B63_30g273 ⚠
conserved hypothetical protein
— OG7
C4B63_163g31 ⚠
conserved hypothetical protein
— OG7
C4B63_89g51 ⚠
FYVE zinc-finger containing protein
— OG7
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_85g63 ⚠
Rab-GTPase-TBC domain containing protein
— OG7
C4B63_30g176 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG7
C4B63_143g33 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_28g123 ⚠
conserved hypothetical protein
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG7
C4B63_56g95 ⚠
paraflagellar rod protein
— OG7
C4B63_1g57 ⚠
AAA ATPase
— OG7
C4B63_14g250 ⚠
Anaphase-promoting complex subunit 3
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.