C4B63_10g125

ankyrin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_126911 OG7: OG7_0000441 116 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 116 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_18g71 ⚠
cyclosome subunit
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_28g122 ⚠
conserved hypothetical protein
— OG7
C4B63_14g782c ⚠
monothiol glutaredoxin
— OG7
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— OG7
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_20g48 ⚠
conserved hypothetical protein
— OG7
C4B63_80g9 ⚠
conserved hypothetical protein
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_99g106 ⚠
monothiol glutaredoxin
— OG7
C4B63_61g21 ⚠
cytidine deaminase-like protein
— OG7
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_19g83 ⚠
Regulatory-associated protein of TOR1
— OG7
C4B63_42g254 ⚠
conserved hypothetical protein
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_23g82 ⚠
conserved hypothetical protein
— OG7
C4B63_46g10 ⚠
Double RNA binding domain protein 6A
— OG7
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_22g166 ⚠
Regulatory-associated protein of mTOR
— OG7
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_32g247 ⚠
conserved hypothetical protein
— OG7
C4B63_10g153 ⚠
RNA-binding protein
— OG7
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG7
C4B63_351g1 ⚠
conserved hypothetical protein
— OG7
C4B63_6g418 ⚠
protein kinase
— OG7
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG7
C4B63_30g176 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_89g51 ⚠
FYVE zinc-finger containing protein
— OG7
C4B63_34g307 ⚠
ubiquitin-conjugating enzyme E2
— OG7
C4B63_263g16 ⚠
Programmed cell death protein 2-like
— OG7
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g352 ⚠
nucleolar GTP-binding protein 1(fragment)
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_7g323 ⚠
conserved hypothetical protein
— OG7
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG7
C4B63_85g63 ⚠
Rab-GTPase-TBC domain containing protein
— OG7
C4B63_32g47 ⚠
RNA-binding protein
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_10g154 ⚠
RNA-binding protein
— OG7
C4B63_16g295 ⚠
RNA-binding protein
— OG7
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_339g2 ⚠
cytidine deaminase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.