C4B63_20g48

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102805 OG7: OG7_0007863 35 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 35 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_69g55 ⚠
monothiol glutaredoxin
— Both
C4B63_46g10 ⚠
Double RNA binding domain protein 6A
— OG7
C4B63_10g153 ⚠
RNA-binding protein
— OG7
C4B63_16g295 ⚠
RNA-binding protein
— OG7
C4B63_10g154 ⚠
RNA-binding protein
— OG7
C4B63_14g50 ⚠
disgorgin
— OG7
C4B63_42g216 ⚠
disgorgin
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_144g24 ⚠
monothiol glutaredoxin
— Both
C4B63_3g1086 ⚠
monothiol glutaredoxin
— OG7
C4B63_14g782c ⚠
monothiol glutaredoxin
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_99g106 ⚠
monothiol glutaredoxin
— OG7
C4B63_24g226 ⚠
protein kinase-like protein
— OG7
C4B63_19g173 ⚠
protein kinase
— OG7
C4B63_14g52
Ubiquitin thioesterase OTU1
— Both
C4B63_9g389 ⚠
ras-related protein Rab21
— OG6
C4B63_10g157 ⚠
Double RNA binding domain protein 6A
— OG6
C4B63_128g53 ⚠
serine/threonine protein phosphatase
— OG6
C4B63_32g47 ⚠
RNA-binding protein
— Both
C4B63_27g214 ⚠
serine/threonine protein phosphatase
— OG6
C4B63_128g54 ⚠
phosphoprotein phosphatase
— OG6
C4B63_61g21 ⚠
cytidine deaminase-like protein
— Both
C4B63_339g2 ⚠
cytidine deaminase-like protein
— Both
C4B63_79g35 ⚠
ras-related protein Rab21
— OG6
C4B63_22g60
homocysteine S-methyltransferase
— Both
C4B63_2g4104c
lactoylglutathione lyase-like protein
— Both
C4B63_34g307
ubiquitin-conjugating enzyme E2
— Both
C4B63_17g232 ⚠
rab11B GTPase,
— OG6
C4B63_148g26 ⚠
rab11B GTPase,
— OG6
C4B63_38g157
palmitoyl acyltransferase 1
— OG6
C4B63_1g52
Dual specificity protein phosphatase 12
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.