C4B63_69g55

monothiol glutaredoxin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101462 OG7: OG7_0003454 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_55g26 ⚠
conserved hypothetical protein
— OG7
C4B63_10g154 ⚠
RNA-binding protein
— OG7
C4B63_8g539 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
C4B63_17g99 ⚠
exportin 1
— OG7
C4B63_142g6 ⚠
GMP synthase
— OG7
C4B63_238g18 ⚠
GMP synthase(fragment)
— OG7
C4B63_14g188 ⚠
UPF0769 protein C21orf59 homolog B
— OG7
C4B63_60g172 ⚠
conserved hypothetical protein
— OG7
C4B63_19g173 ⚠
protein kinase
— OG7
C4B63_24g226 ⚠
protein kinase-like protein
— OG7
C4B63_114g20 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic
— OG7
C4B63_16g295 ⚠
RNA-binding protein
— OG7
C4B63_10g153 ⚠
RNA-binding protein
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_46g10 ⚠
Double RNA binding domain protein 6A
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_89g43 ⚠
PITH domain-containing protein
— OG7
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— OG7
C4B63_110g27 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_2g486 ⚠
Serine-threonine kinase receptor-associated p
— OG7
C4B63_39g333 ⚠
eukaryotic translation initiation factor 3 su
— OG7
C4B63_252g23 ⚠
Serine-threonine kinase receptor-associated p
— OG7
C4B63_14g35 ⚠
Sucrase/ferredoxin-like
— OG7
C4B63_241g7 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_17g233 ⚠
iron superoxide dismutase
— OG7
C4B63_25g240 ⚠
Macro domain containing protein
— OG7
C4B63_148g27 ⚠
iron superoxide dismutase
— OG7
C4B63_9g488 ⚠
conserved hypothetical protein
— OG7
C4B63_225g44 ⚠
conserved hypothetical protein
— OG7
C4B63_9g448 ⚠
superoxide dismutase
— OG7
C4B63_219g40 ⚠
Leucine-rich repeat-containing protein
— OG7
C4B63_219g55 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_236g16 ⚠
Leucine-rich repeat-containing protein 34
— OG7
C4B63_392g17 ⚠
iron superoxide dismutase
— OG7
C4B63_80g53 ⚠
iron superoxide dismutase
— OG7
C4B63_31g85 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
C4B63_1g52 ⚠
Dual specificity protein phosphatase 12
— OG6
C4B63_33g10 ⚠
EEF1A lysine methyltransferase 4
— OG7
C4B63_72g86 ⚠
EEF1A lysine methyltransferase 4
— OG7
C4B63_17g188 ⚠
Phosphopantetheine adenylyltransferase
— OG7
C4B63_4g348 ⚠
Bifunctional coenzyme A synthase
— OG7
C4B63_112g17 ⚠
conserved hypothetical protein
— OG7
C4B63_58g136 ⚠
conserved hypothetical protein
— OG7
C4B63_58g137 ⚠
conserved hypothetical protein
— OG7
C4B63_32g47 ⚠
RNA-binding protein
— Both
C4B63_148g26 ⚠
rab11B GTPase,
— OG6
C4B63_29g6 ⚠
EEF1A lysine methyltransferase 4
— OG7
C4B63_339g2 ⚠
cytidine deaminase-like protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.