C4B63_48g23

nicotinate phosphoribosyltransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_109462 OG7: OG7_0015320 207 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 207 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g177 ⚠
UPF0652 protein
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_112g17
conserved hypothetical protein
— Both
C4B63_58g136 ⚠
conserved hypothetical protein
— Both
C4B63_58g137 ⚠
conserved hypothetical protein
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_35g191
6-phosphogluconolactonase
— Both
C4B63_4g357
Activator of 90 kDa heat shock protein ATPase
— Both
C4B63_99g106 ⚠
monothiol glutaredoxin
— Both
C4B63_241g7 ⚠
Leucine-rich repeat-containing protein 34
— Both
C4B63_11g25
conserved hypothetical protein
— Both
C4B63_20g213 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_188g43
conserved hypothetical protein
— Both
C4B63_184g9 ⚠
protein phosphatase 2C
— OG6
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_4g383 ⚠
mevalonate-diphosphate decarboxylase
— Both
C4B63_58g38 ⚠
conserved hypothetical protein
— Both
C4B63_21g282
mitogen-activated protein kinase 3
— OG6
C4B63_31g228 ⚠
dihydroorotase
— Both
C4B63_17g233 ⚠
iron superoxide dismutase
— Both
C4B63_31g106
conserved hypothetical protein
— Both
C4B63_14g782c ⚠
monothiol glutaredoxin
— Both
C4B63_25g240
Macro domain containing protein
— Both
C4B63_227g9 ⚠
mevalonate-diphosphate decarboxylase
— Both
C4B63_2g294
40 kDa cyclophilin
— OG6
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— Both
C4B63_2g486 ⚠
Serine-threonine kinase receptor-associated p
— Both
C4B63_31g85 ⚠
iron superoxide dismutase A, mitochondrial
— Both
C4B63_13g192 ⚠
Elongation factor G1, mitochondrial
— Both
C4B63_60g80 ⚠
dihydroorotase
— Both
C4B63_20g212 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— Both
C4B63_80g53 ⚠
iron superoxide dismutase
— Both
C4B63_392g17 ⚠
iron superoxide dismutase
— Both
C4B63_47g40 ⚠
CS domain containing protein
— Both
C4B63_219g55 ⚠
Leucine-rich repeat-containing protein 34
— Both
C4B63_90g47 ⚠
UPF0652 protein
— Both
C4B63_10g488
UBX domain-containing protein
— Both
C4B63_148g27 ⚠
iron superoxide dismutase
— Both
C4B63_7g133
pyroglutamyl-peptidase I
— Both
C4B63_13g230
Eukaryotic translation initiation factor 6
— Both
C4B63_219g40 ⚠
Leucine-rich repeat-containing protein
— Both
C4B63_79g87
phosphoglucomutase
— Both
C4B63_4g226
UTP-glucose-1-phosphate uridylyltransferase 2
— Both
C4B63_89g43
PITH domain-containing protein
— Both
C4B63_259g9 ⚠
Ran-binding protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.