C4B63_24g272

Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain (ubiquitin-transferase)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146743 OG7: OG7_0043053 255 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 255 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g126 ⚠
conserved hypothetical protein
— Both
C4B63_122g17 ⚠
conserved hypothetical protein
— OG7
C4B63_7g383 ⚠
epsilon-adaptin
— OG7
C4B63_87g11 ⚠
epsilon-adaptin(fragment)
— OG7
C4B63_136g39 ⚠
conserved hypothetical protein
— OG7
C4B63_26g318 ⚠
conserved hypothetical protein
— OG7
C4B63_175g10 ⚠
aldo/keto reductase
— OG7
C4B63_4g348 ⚠
Bifunctional coenzyme A synthase
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_43g211 ⚠
conserved hypothetical protein
— OG7
C4B63_43g210 ⚠
conserved hypothetical protein
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_11g83 ⚠
Eukaryotic translation initiation factor 3 su
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— Both
C4B63_286g18 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— Both
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— Both
C4B63_7g421 ⚠
coatomer alpha subunit
— Both
C4B63_175g12 ⚠
conserved hypothetical protein
— Both
C4B63_63g10 ⚠
conserved hypothetical protein
— Both
C4B63_63g7 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_2g411 ⚠
conserved hypothetical protein
— Both
C4B63_14g219 ⚠
Pre-mRNA-splicing factor prp5
— Both
C4B63_80g31 ⚠
Dynein assembly factor 4, axonemal
— Both
C4B63_6g279 ⚠
Coatomer subunit gamma
— Both
C4B63_20g319 ⚠
25 kDa translation elongation factor 1-beta
— Both
C4B63_286g21 ⚠
conserved hypothetical protein
— Both
C4B63_37g159 ⚠
mucin TcMUCII
— OG6
C4B63_52g168 ⚠
Cilia- and flagella-associated protein 44
— Both
C4B63_39g160 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_17g188 ⚠
Phosphopantetheine adenylyltransferase
— Both
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— Both
C4B63_30g145 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_16g163 ⚠
Pyridoxal phosphate homeostasis protein
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— Both
C4B63_21g277 ⚠
conserved hypothetical protein
— Both
C4B63_23g200 ⚠
Flagellum attachment zone protein 19
— Both
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_69g27 ⚠
35 kDa cyclophilin
— OG6
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_76g57 ⚠
Tripartite attachment complex protein 102
— Both
C4B63_9g306 ⚠
dynein intermediate chain
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.