C4B63_80g31

Dynein assembly factor 4, axonemal
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105298 OG7: OG7_0010785 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g264 ⚠
Protein kintoun
— Both
C4B63_4g265 ⚠
pre-RNA processing PIH1/Nop17
— OG7
C4B63_2g215 ⚠
PIH1 domain-containing protein 1
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— Both
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_2g61 ⚠
conserved hypothetical protein
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_2g63 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_2g62 ⚠
conserved hypothetical protein
— OG7
C4B63_2g60 ⚠
conserved hypothetical protein
— OG7
C4B63_54g50
conserved hypothetical protein
— OG7
C4B63_19g120 ⚠
conserved hypothetical protein
— OG7
C4B63_19g121 ⚠
conserved hypothetical protein
— OG7
C4B63_10g280 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_23g143 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_136g39 ⚠
conserved hypothetical protein
— OG7
C4B63_26g318 ⚠
conserved hypothetical protein
— OG7
C4B63_6g279 ⚠
Coatomer subunit gamma
— Both
C4B63_137g44 ⚠
receptor for activated C kinase 1
— OG7
C4B63_49g74 ⚠
MORN repeat-containing protein 5
— OG7
C4B63_481g13 ⚠
MORN repeat-containing protein 5
— OG7
C4B63_137g45 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g46 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g47 ⚠
receptor for activated C kinase 1
— OG7
C4B63_6g321 ⚠
receptor for activated C kinase 1
— OG7
C4B63_113g53
trans-splicing factor
— Both
C4B63_6g320 ⚠
receptor for activated C kinase 1
— OG7
C4B63_18g223
eukaryotic translation initiation factor 3 su
— Both
C4B63_137g48 ⚠
receptor for activated C kinase 1
— OG7
C4B63_18g20 ⚠
Protein will die slowly
— OG7
C4B63_137g10 ⚠
Coatomer subunit gamma
— Both
C4B63_38g158 ⚠
Poly(A) RNA polymerase cid14
— OG7
C4B63_45g105 ⚠
DNA polymerase sigma
— OG7
C4B63_8g520 ⚠
DNA polymerase sigma-like protein
— OG7
C4B63_41g138 ⚠
myotubularin
— OG7
C4B63_93g92 ⚠
Myotubularin-related protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.