C4B63_34g361

phosphatidylinositol kinase related protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102827 OG7: OG7_0001934 381 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 381 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_23g143 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_326g16 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_358g1 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_249g23 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_249g22 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_326g15 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_10g280 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_80g31 ⚠
Dynein assembly factor 4, axonemal
— OG7
C4B63_40g114 ⚠
glycosyl hydrolase
— OG7
C4B63_13g334 ⚠
conserved hypothetical protein
— Both
C4B63_12g196 ⚠
conserved hypothetical protein
— OG7
C4B63_128g60 ⚠
zinc-finger protein family member
— OG7
C4B63_12g8 ⚠
conserved hypothetical protein
— OG7
C4B63_7g245 ⚠
ribosomal protein L3
— OG7
C4B63_7g242 ⚠
ribosomal protein L3
— OG7
C4B63_7g243 ⚠
ribosomal protein L3
— OG7
C4B63_7g240 ⚠
ribosomal protein L3
— OG7
C4B63_7g244 ⚠
ribosomal protein L3
— OG7
C4B63_7g241 ⚠
ribosomal protein L3
— OG7
C4B63_93g92 ⚠
Myotubularin-related protein
— OG7
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG7
C4B63_41g138 ⚠
myotubularin
— OG7
C4B63_56g93 ⚠
Splicing factor 3B subunit 3
— OG7
C4B63_354g7 ⚠
damage-specific DNA binding protein
— OG7
C4B63_247g23 ⚠
damage-specific DNA binding protein
— OG7
C4B63_18g183 ⚠
damage-specific DNA binding protein
— OG7
C4B63_354g8 ⚠
damage-specific DNA binding protein
— OG7
C4B63_30g190 ⚠
60S ribosomal protein L23a
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_2g61 ⚠
conserved hypothetical protein
— OG7
C4B63_4g111 ⚠
conserved hypothetical protein
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— OG7
C4B63_72g101 ⚠
AMP deaminase(fragment)
— OG7
C4B63_2g735 ⚠
acyl transferase-like protein
— OG7
C4B63_14g87 ⚠
conserved hypothetical protein
— OG7
C4B63_2g62 ⚠
conserved hypothetical protein
— OG7
C4B63_42g168 ⚠
CDC16
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_63g93 ⚠
Cell division control protein 48
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_2g63 ⚠
conserved hypothetical protein
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.