C4B63_14g103

beta adaptin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105105 OG7: OG7_0001921 230 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 230 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g395 ⚠
conserved hypothetical protein
— OG7
C4B63_107g4 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
C4B63_128g59 ⚠
dihydrolipoamide branched chain transacylase
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_10g522 ⚠
FACT complex subunit SPT16
— OG7
C4B63_26g245 ⚠
inositol/phosphatidylinositol phosphatase
— OG7
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_54g57 ⚠
vacuolar ATP synthase subunit d
— OG7
C4B63_13g257 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_2g513 ⚠
conserved hypothetical protein
— OG7
C4B63_39g359 ⚠
conserved hypothetical protein
— OG7
C4B63_23g143 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_72g79 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_31g76 ⚠
ubiquitin-activating enzyme
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG7
C4B63_4g116 ⚠
FACT complex subunit ssrp1-B
— OG7
C4B63_4g342 ⚠
ATP synthase mitochondrial F1 complex assembl
— OG7
C4B63_11g484 ⚠
Leucine Rich Repeat protein
— OG7
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_22g11 ⚠
developmentally regulated phosphoprotein
— OG7
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— OG7
C4B63_8g44 ⚠
conserved hypothetical protein
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG7
C4B63_11g100 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
C4B63_32g239 ⚠
tubulin folding cofactor D
— OG7
C4B63_72g94 ⚠
ribosomal RNA processing protein 40
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_40g156 ⚠
Alkylated DNA repair dioxygenase AlkB
— OG7
C4B63_32g232 ⚠
conserved hypothetical protein
— OG7
C4B63_127g51 ⚠
acetyl-CoA carboxylase
— OG7
C4B63_7g234 ⚠
Signal recognition particle subunit SRP68
— OG7
C4B63_44g236 ⚠
conserved hypothetical protein
— OG7
C4B63_4g201 ⚠
Protein ILITYHIA
— OG7
C4B63_4g200 ⚠
conserved hypothetical protein
— OG7
C4B63_43g196 ⚠
adenylate kinase 1
— OG7
C4B63_4g202 ⚠
Periodic tryptophan protein 2 homolog
— OG7
C4B63_192g4 ⚠
adenylate kinase 1
— OG7
C4B63_42g232 ⚠
ubiquitin hydrolase
— OG7
C4B63_192g23 ⚠
conserved hypothetical protein
— OG7
C4B63_21g30 ⚠
Exportin-7-A
— OG7
C4B63_4g170 ⚠
Cilia- and flagella-associated protein 74
— OG7
C4B63_48g37 ⚠
conserved hypothetical protein
— OG7
C4B63_24g190 ⚠
Exportin-7
— OG7
C4B63_85g64 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.