C4B63_2g376

ribosome assembly protein RRB1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_102504 OG7: OG7_0007856 270 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 270 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g320 ⚠
conserved hypothetical protein
— Both
C4B63_31g76 ⚠
ubiquitin-activating enzyme
— Both
C4B63_4g258 ⚠
prolyl-tRNA synthetase
— Both
C4B63_85g75 ⚠
ubiquitin activating enzyme
— OG7
C4B63_31g99 ⚠
WD repeat-containing protein 17
— Both
C4B63_76g32 ⚠
guide RNA associated protein, GAP2
— Both
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— Both
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— Both
C4B63_4g269 ⚠
conserved hypothetical protein
— Both
C4B63_42g187 ⚠
conserved hypothetical protein
— Both
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_42g99 ⚠
E3 ubiquitin-protein ligase HEL2
— Both
C4B63_52g51 ⚠
serine/threonine protein kinase
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_25g120 ⚠
Protein kinase domain
— OG7
C4B63_137g49 ⚠
conserved hypothetical protein
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_2g336 ⚠
Proteinaceous RNase P 2
— OG7
C4B63_26g245 ⚠
inositol/phosphatidylinositol phosphatase
— OG7
C4B63_13g113 ⚠
zinc-finger of a C2HC-type
— OG7
C4B63_56g88 ⚠
Zinc finger C2HC domain-containing protein 1C
— OG7
C4B63_13g257 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_2g365 ⚠
dual-specificity protein kinase
— OG7
C4B63_61g59 ⚠
Protein kinase domain
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_42g42 ⚠
co-chaperone GrpE
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_43g137 ⚠
pumilio/PUF RNA binding protein 3
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_13g170 ⚠
pumilio/PUF RNA binding protein 1
— OG7
C4B63_24g190 ⚠
Exportin-7
— Both
C4B63_54g57 ⚠
vacuolar ATP synthase subunit d
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_21g30 ⚠
Exportin-7-A
— Both
C4B63_27g3 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_93g65 ⚠
amidohydrolase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.