C4B63_47g49

tRNA pseudouridine synthase 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101974 OG7: OG7_0002342 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— Both
C4B63_22g77 ⚠
conserved hypothetical protein
— OG7
C4B63_41g148 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_439g12 ⚠
pumilio/PUF RNA binding protein 4
— OG7
C4B63_13g170 ⚠
pumilio/PUF RNA binding protein 1
— OG7
C4B63_97g23 ⚠
pumilio/PUF RNA binding protein 2
— OG7
C4B63_43g137 ⚠
pumilio/PUF RNA binding protein 3
— OG7
C4B63_13g295 ⚠
pumilio/PUF RNA binding protein 6
— OG7
C4B63_4g494 ⚠
conserved hypothetical protein
— OG7
C4B63_314g10 ⚠
5'-AMP-activated protein kinase subunit beta
— OG7
C4B63_16g11 ⚠
5'-AMP-activated protein kinase subunit beta
— OG7
C4B63_8g190 ⚠
conserved hypothetical protein
— OG7
C4B63_197g36 ⚠
conserved hypothetical protein
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_61g59 ⚠
Protein kinase domain
— OG7
C4B63_48g106 ⚠
Ribosomal protein S5, C-terminal domain conta
— OG7
C4B63_40g23 ⚠
vacuolar protein sorting-associated protein-l
— OG7
C4B63_2g365 ⚠
dual-specificity protein kinase
— OG7
C4B63_56g88 ⚠
Zinc finger C2HC domain-containing protein 1C
— OG7
C4B63_13g113 ⚠
zinc-finger of a C2HC-type
— OG7
C4B63_2g354 ⚠
isopentenyl-diphosphate delta-isomerase
— OG7
C4B63_25g120 ⚠
Protein kinase domain
— OG7
C4B63_52g51 ⚠
serine/threonine protein kinase
— OG7
C4B63_8g540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_52g128 ⚠
protein kinase
— OG7
C4B63_19g264 ⚠
conserved hypothetical protein
— OG7
C4B63_40g122 ⚠
vacuolar protein sorting-associated protein-l
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_84g63 ⚠
conserved hypothetical protein
— OG7
C4B63_391g15 ⚠
conserved hypothetical protein
— OG7
C4B63_18g312 ⚠
conserved hypothetical protein
— OG7
C4B63_14g158 ⚠
serine/threonine kinase
— OG7
C4B63_102g53 ⚠
conserved hypothetical protein
— OG7
C4B63_52g127 ⚠
protein kinase
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_45g128 ⚠
conserved hypothetical protein
— OG7
C4B63_45g130 ⚠
conserved hypothetical protein
— OG7
C4B63_45g129 ⚠
conserved hypothetical protein
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_52g143 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
C4B63_188g44 ⚠
conserved hypothetical protein
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_28g61 ⚠
Methyltransferase-like protein 17, mitochondr
— OG7
C4B63_6g439 ⚠
tRNA pseudouridine synthase
— OG7
C4B63_20g184 ⚠
Pseudouridylate synthase 7 homolog-like prote
— OG7
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_40g27 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.