C4B63_56g88

Zinc finger C2HC domain-containing protein 1C
Trypanosoma cruzi Dm28c 2018 OG6: OG6_215282 OG7: OG7_0005202 66 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 66 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_70g126 ⚠
conserved hypothetical protein
— OG7
C4B63_95g23 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
C4B63_2g799 ⚠
tRNA wybutosine-synthesizing protein 4
— OG7
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_8g540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_23g264 ⚠
6-phosphofructo-2-kinase 1
— OG7
C4B63_45g121 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_54g80 ⚠
conserved hypothetical protein
— OG7
C4B63_76g32 ⚠
guide RNA associated protein, GAP2
— OG7
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— OG7
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— OG7
C4B63_85g64 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
C4B63_32g239 ⚠
tubulin folding cofactor D
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG7
C4B63_44g120 ⚠
conserved hypothetical protein
— OG7
C4B63_133g51 ⚠
heat shock protein 70
— OG7
C4B63_18g202 ⚠
conserved hypothetical protein
— OG7
C4B63_7g347 ⚠
V-type ATPase, A subunit
— OG7
C4B63_14g144 ⚠
branch point binding protein
— OG7
C4B63_310g13 ⚠
branch point binding protein
— OG7
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_43g175 ⚠
2-oxoisovalerate dehydrogenase alpha subunit
— OG7
C4B63_21g247 ⚠
conserved hypothetical protein
— OG7
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_4g258 ⚠
prolyl-tRNA synthetase
— OG7
C4B63_25g120 ⚠
Protein kinase domain
— OG7
C4B63_10g522 ⚠
FACT complex subunit SPT16
— OG7
C4B63_39g357 ⚠
ATP synthase
— OG7
C4B63_52g51 ⚠
serine/threonine protein kinase
— OG7
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_11g475 ⚠
COP9 signalosome complex subunit 2
— OG7
C4B63_2g365 ⚠
dual-specificity protein kinase
— OG7
C4B63_4g320 ⚠
conserved hypothetical protein
— OG7
C4B63_61g59 ⚠
Protein kinase domain
— OG7
C4B63_43g186 ⚠
ATP synthase
— OG7
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.