C4B63_8g527

pseudouridylate synthase I
Trypanosoma cruzi Dm28c 2018 OG6: OG6_133986 OG7: OG7_0002342 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_32g239 ⚠
tubulin folding cofactor D
— OG7
C4B63_391g15 ⚠
conserved hypothetical protein
— OG7
C4B63_18g312 ⚠
conserved hypothetical protein
— OG7
C4B63_392g12 ⚠
conserved hypothetical protein
— OG7
C4B63_4g269 ⚠
conserved hypothetical protein
— OG7
C4B63_43g143 ⚠
protein kinase
— OG7
C4B63_14g158 ⚠
serine/threonine kinase
— OG7
C4B63_102g53 ⚠
conserved hypothetical protein
— OG7
C4B63_52g127 ⚠
protein kinase
— OG7
C4B63_227g4 ⚠
Zinc finger protein 474
— OG7
C4B63_70g117 ⚠
Putative tRNA pseudouridine synthase Pus10
— OG7
C4B63_95g23 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_45g128 ⚠
conserved hypothetical protein
— OG7
C4B63_45g130 ⚠
conserved hypothetical protein
— OG7
C4B63_70g126 ⚠
conserved hypothetical protein
— OG7
C4B63_45g129 ⚠
conserved hypothetical protein
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_21g264 ⚠
protein transport protein SEC23
— OG7
C4B63_22g77 ⚠
conserved hypothetical protein
— OG7
C4B63_58g128 ⚠
conserved hypothetical protein
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_76g32 ⚠
guide RNA associated protein, GAP2
— OG7
C4B63_93g65 ⚠
amidohydrolase
— OG7
C4B63_93g64 ⚠
amidohydrolase
— OG7
C4B63_4g181 ⚠
Sestrin-3
— OG7
C4B63_28g165 ⚠
conserved hypothetical protein
— OG7
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— OG7
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— OG7
C4B63_188g44 ⚠
conserved hypothetical protein
— OG7
C4B63_9g489 ⚠
conserved hypothetical protein
— OG7
C4B63_44g113 ⚠
conserved hypothetical protein
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_14g82 ⚠
pseudouridine synthase TruD
— OG7
C4B63_28g61 ⚠
Methyltransferase-like protein 17, mitochondr
— OG7
C4B63_20g184 ⚠
Pseudouridylate synthase 7 homolog-like prote
— OG7
C4B63_6g439 ⚠
tRNA pseudouridine synthase
— OG7
C4B63_75g61 ⚠
calmodulin
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.