C4B63_70g126

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_172363 OG7: OG7_0062553 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_13g166 ⚠
leucine carboxyl methyltransferase
— OG7
C4B63_42g221
kinesin
— OG6
C4B63_44g120
conserved hypothetical protein
— Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— +2 more Both
C4B63_101g15
serine peptidase, Clan SC, Family S9B
— Both
C4B63_85g64
DNA-damage inducible protein DDI1-like protei
— Both
C4B63_42g99
E3 ubiquitin-protein ligase HEL2
— Both
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_43g143 ⚠
protein kinase
— Both
C4B63_4g269
conserved hypothetical protein
— Both
C4B63_7g77
conserved hypothetical protein
— Both
C4B63_6g258 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_6g257 ⚠
Vacuolar proton pump subunit B
— Both
C4B63_3g1104
threonyl-tRNA synthetase
— Both
C4B63_297g14 ⚠
phenylalanyl-tRNA synthetase alpha chain
— Both
C4B63_7g395
conserved hypothetical protein
— Both
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— Both
C4B63_153g41 ⚠
inositol 5-phosphatase 1(fragment)
— Both
C4B63_21g30 ⚠
Exportin-7-A
— Both
C4B63_7g417
snoRNP protein GAR1
— Both
C4B63_27g4 ⚠
ubiquitin ligase
— Both
C4B63_2g748
conserved hypothetical protein
— Both
C4B63_227g4 ⚠
Zinc finger protein 474
— Both
C4B63_42g49
Protein aardvark
— Both
C4B63_76g41
Probable S-adenosyl-L-methionine-binding prot
— Both
C4B63_32g256 ⚠
PFU (PLAA family ubiquitin binding)
— Both
C4B63_32g255 ⚠
WD domain, G-beta repeat
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_76g32
guide RNA associated protein, GAP2
— Both
C4B63_32g239 ⚠
tubulin folding cofactor D
— Both
C4B63_32g238 ⚠
tubulin folding cofactor D
— Both
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_12g219 ⚠
adaptin-related protein-like
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_2g203 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_52g128 ⚠
protein kinase
— OG7
C4B63_19g264 ⚠
conserved hypothetical protein
— OG7
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_52g127 ⚠
protein kinase
— OG7
C4B63_28g111 ⚠
synaptojanin
— OG7
C4B63_14g158 ⚠
serine/threonine kinase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.