C4B63_2g748

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146720 OG7: OG7_0043234 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g417
snoRNP protein GAR1
— Both
C4B63_63g32 ⚠
adaptin-related protein-like
— Both
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g552 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g550 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_54g71 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_15g19 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g554 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— Both
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— Both
C4B63_7g395
conserved hypothetical protein
— Both
C4B63_16g105
coronin
— Both
C4B63_2g566
phenylalanyl-tRNA synthetase
— Both
C4B63_17g69 ⚠
phenylalanyl-tRNA synthetase alpha chain
— Both
C4B63_297g14 ⚠
phenylalanyl-tRNA synthetase alpha chain
— Both
C4B63_7g77
conserved hypothetical protein
— Both
C4B63_42g221
kinesin
— OG6
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_70g126
conserved hypothetical protein
— Both
C4B63_2g513
conserved hypothetical protein
— Both
C4B63_10g522
FACT complex subunit SPT16
— Both
C4B63_128g59
dihydrolipoamide branched chain transacylase
— Both
C4B63_122g21 ⚠
ubiquitin ligase
— Both
C4B63_7g134
conserved hypothetical protein
— Both
C4B63_21g247
conserved hypothetical protein
— Both
C4B63_149g26
GDP-mannose pyrophosphorylase
— Both
C4B63_38g169 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_22g11 ⚠
developmentally regulated phosphoprotein
— Both
C4B63_31g99
WD repeat-containing protein 17
— Both
C4B63_21g259
Small RNA degrading nuclease 5
— Both
C4B63_43g126
ATP synthase F1 subunit gamma protein
— Both
C4B63_153g40 ⚠
inositol 5-phosphatase 1
— Both
C4B63_11g484
Leucine Rich Repeat protein
— Both
C4B63_4g342
ATP synthase mitochondrial F1 complex assembl
— Both
C4B63_4g116
FACT complex subunit ssrp1-B
— Both
C4B63_22g164 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_31g76 ⚠
ubiquitin-activating enzyme
— Both
C4B63_39g359
conserved hypothetical protein
— Both
C4B63_72g79 ⚠
inositol 5-phosphatase 1
— Both
C4B63_4g422
C-terminal motor kinesin
— OG6
C4B63_101g15
serine peptidase, Clan SC, Family S9B
— Both
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_3g1104
threonyl-tRNA synthetase
— Both
C4B63_153g41 ⚠
inositol 5-phosphatase 1(fragment)
— Both
C4B63_27g4 ⚠
ubiquitin ligase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.