C4B63_31g99

WD repeat-containing protein 17

Trypanosoma cruzi Dm28c 2018 OG6: OG6_107301 OG7: OG7_0010331 229 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 229 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_41g122 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	OG7
C4B63_168g16 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	OG7
C4B63_102g61 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	OG7
C4B63_42g203 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	OG7
C4B63_42g202 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	OG7
C4B63_32g239 ⚠ tubulin folding cofactor D	—	OG6 LdBPK_080420.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010560	Both
C4B63_42g187 conserved hypothetical protein	—	OG6 LdBPK_080420.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_300580.1	Both
C4B63_4g320 conserved hypothetical protein	—	OG6 Tb927.10.14030 ↔ Tb927.5.3260 OG6 LdBPK_080420.1 ↔ LdBPK_180550.1 OG7 Tb927.10.14030 ↔ Tb927.5.3260 OG7 LdBPK_080420.1 ↔ LdBPK_180550.1	Both
C4B63_85g75 ⚠ ubiquitin activating enzyme	—	OG7 LdBPK_080230.1 ↔ LdBPK_080420.1 OG7 TCSYLVIO_010542 ↔ TCSYLVIO_010560	OG7
C4B63_2g376 ⚠ ribosome assembly protein RRB1	—	OG6 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_332020.1 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_332020.1	Both
C4B63_271g10 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_332020.1	OG7
C4B63_41g128 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	OG7
C4B63_224g16 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	OG7
C4B63_41g125 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	OG7
C4B63_43g202 ⚠ hook complex protein, conserved	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_332020.1	OG7
C4B63_7g79 ⚠ aspartyl-tRNA synthetase	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	Both
C4B63_41g119 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	OG7
C4B63_2g450 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	OG7
C4B63_2g566 phenylalanyl-tRNA synthetase	—	OG6 TCSYLVIO_005548 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_191010.1 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_191010.1	Both
C4B63_31g76 ⚠ ubiquitin-activating enzyme	—	OG6 LdBPK_080230.1 ↔ LdBPK_080420.1 OG6 TCSYLVIO_010542 ↔ TCSYLVIO_010560 OG7 LdBPK_080230.1 ↔ LdBPK_080420.1 OG7 TCSYLVIO_010542 ↔ TCSYLVIO_010560	Both
C4B63_193g9 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
C4B63_70g129 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
C4B63_12g153 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
C4B63_32g238 ⚠ tubulin folding cofactor D	—	OG6 LdBPK_080420.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010560	Both
C4B63_26g245 ⚠ inositol/phosphatidylinositol phosphatase	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
C4B63_32g255 ⚠ WD domain, G-beta repeat	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_010560	Both
C4B63_252g9 ⚠ ubiquitin carboxyl-terminal hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_010560	OG7
C4B63_2g502 ⚠ ubiquitin carboxyl-terminal hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_010560	OG7
C4B63_2g83 ⚠ ubiquitin hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_010560	OG7
C4B63_78g11 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
C4B63_78g12 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
C4B63_234g11 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
C4B63_173g6 ⚠ Soluble NSF attachment protein, SNAP (parafla	—	OG6 LdBPK_020280.1 ↔ LdBPK_080420.1 OG7 LdBPK_020280.1 ↔ LdBPK_080420.1	Both
C4B63_34g375 ⚠ Soluble NSF attachment protein, SNAP (parafla	—	OG6 LdBPK_020280.1 ↔ LdBPK_080420.1 OG7 LdBPK_020280.1 ↔ LdBPK_080420.1	Both
C4B63_78g9 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
C4B63_78g13 ⚠ Proteasome activator complex subunit 4	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
C4B63_78g10 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
C4B63_4g116 FACT complex subunit ssrp1-B	—	OG6 TCSYLVIO_006113 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_006113 ↔ TCSYLVIO_010560	Both
C4B63_2g75 ⚠ poly(A)-specific ribonuclease PARN(fragment)	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_010560	OG7
C4B63_2g74 ⚠ poly(A)-specific ribonuclease PARN(fragment)	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_010560	OG7
C4B63_396g8 ⚠ synaptojanin (N-terminal domain)	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
C4B63_28g111 ⚠ synaptojanin	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
C4B63_20g38 ⚠ Synaptojanin	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
C4B63_122g21 ⚠ ubiquitin ligase	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_010560	Both
C4B63_21g30 ⚠ Exportin-7-A	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_010560	Both
C4B63_39g359 conserved hypothetical protein	—	OG6 TCSYLVIO_009198 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009198 ↔ TCSYLVIO_010560	Both
C4B63_11g484 Leucine Rich Repeat protein	—	OG6 TCSYLVIO_006421 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_006421 ↔ TCSYLVIO_010560	Both
C4B63_27g4 ⚠ ubiquitin ligase	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_010560	Both
C4B63_149g26 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010560	Both
C4B63_2g289 ⚠ Hypoxia up-regulated protein 1 (Fragment)	—	OG6 Tb927.5.3260 ↔ Tb927.9.9860	OG6

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