C4B63_2g75

poly(A)-specific ribonuclease PARN(fragment)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_128943 OG7: OG7_0005534 213 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 213 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_4g235 ⚠
5-oxoprolinase
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_4g234 ⚠
5-oxoprolinase
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_22g11 ⚠
developmentally regulated phosphoprotein
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— OG7
C4B63_32g239 ⚠
tubulin folding cofactor D
— OG7
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_153g41 ⚠
inositol 5-phosphatase 1(fragment)
— OG7
C4B63_7g395 ⚠
conserved hypothetical protein
— OG7
C4B63_297g14 ⚠
phenylalanyl-tRNA synthetase alpha chain
— OG7
C4B63_3g1104 ⚠
threonyl-tRNA synthetase
— OG7
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— OG7
C4B63_2g203 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_7g77 ⚠
conserved hypothetical protein
— OG7
C4B63_20g6 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_28g111 ⚠
synaptojanin
— OG7
C4B63_85g64 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
C4B63_2g785 ⚠
conserved hypothetical protein
— OG7
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_7g161 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g169 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g173 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_85g75 ⚠
ubiquitin activating enzyme
— OG7
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_31g99 ⚠
WD repeat-containing protein 17
— OG7
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_54g70 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_11g71 ⚠
conserved hypothetical protein
— OG7
C4B63_153g40 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_21g259 ⚠
Small RNA degrading nuclease 5
— OG7
C4B63_43g126 ⚠
ATP synthase F1 subunit gamma protein
— OG7
C4B63_16g105 ⚠
coronin
— OG7
C4B63_13g160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
C4B63_3g551 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_17g69 ⚠
phenylalanyl-tRNA synthetase alpha chain
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.