C4B63_22g11

developmentally regulated phosphoprotein

Trypanosoma cruzi Dm28c 2018 OG6: OG6_100725 OG7: OG7_0002830 170 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 170 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_23g186 ⚠ aspartyl aminopeptidase	—	OG7 LdBPK_240010.1 ↔ LdBPK_292470.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_004406	OG7
C4B63_41g122 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977	OG7
C4B63_41g125 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977	OG7
C4B63_224g16 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977	OG7
C4B63_41g119 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977	OG7
C4B63_41g128 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977	OG7
C4B63_32g238 ⚠ tubulin folding cofactor D	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007262	Both
C4B63_32g239 ⚠ tubulin folding cofactor D	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007262	Both
C4B63_7g377 ⚠ [Pyruvate dehydrogenase (acetyl-transferring)	—	OG7 Tb927.1.1000 ↔ Tb927.11.4780 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007262	OG7
C4B63_2g74 ⚠ poly(A)-specific ribonuclease PARN(fragment)	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 LdBPK_230660.1 ↔ LdBPK_240010.1	OG7
C4B63_2g75 ⚠ poly(A)-specific ribonuclease PARN(fragment)	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 LdBPK_230660.1 ↔ LdBPK_240010.1	OG7
C4B63_42g202 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
C4B63_42g203 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
C4B63_168g16 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
C4B63_102g61 ⚠ aspartyl-tRNA synthetase	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
C4B63_63g95 ⚠ poly(A)-specific ribonuclease PARN	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 LdBPK_230660.1 ↔ LdBPK_240010.1	Both
C4B63_16g30 ⚠ poly(A)-specific ribonuclease PARN	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 LdBPK_230660.1 ↔ LdBPK_240010.1	Both
C4B63_160g6 ⚠ poly(A)-specific ribonuclease PARN	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007262 OG7 LdBPK_230660.1 ↔ LdBPK_240010.1	Both
C4B63_7g79 ⚠ aspartyl-tRNA synthetase	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	Both
C4B63_28g25 ⚠ pyruvate dehydrogenase (lipoamide) kinase	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_007262 OG6 Tb927.1.1000 ↔ Tb927.11.4780 OG7 Tb927.1.1000 ↔ Tb927.11.4780 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007262	Both
C4B63_2g566 ⚠ phenylalanyl-tRNA synthetase	—	OG6 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_240010.1	Both
C4B63_4g235 ⚠ 5-oxoprolinase	—	OG7 LdBPK_181050.1 ↔ LdBPK_240010.1	OG7
C4B63_28g93 ⚠ DeSI-like protein At4g17486	—	OG7 LdBPK_240010.1 ↔ LdBPK_240660.1	OG7
C4B63_11g75 ⚠ Leucine-rich repeat-containing protein 72	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006116	OG7
C4B63_4g509 ⚠ FKBP-type peptidylprolyl cis-trans isomerase	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005957	OG7
C4B63_252g9 ⚠ ubiquitin carboxyl-terminal hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005373 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005374	OG7
C4B63_2g502 ⚠ ubiquitin carboxyl-terminal hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005373 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005374	OG7
C4B63_293g30c ⚠ peptidyl-prolyl cis-trans isomerase	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005957	OG7
C4B63_2g83 ⚠ ubiquitin hydrolase	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005373 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005374	OG7
C4B63_78g11 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_240010.1	OG7
C4B63_78g12 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_240010.1	OG7
C4B63_234g11 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_240010.1	OG7
C4B63_78g9 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_240010.1	OG7
C4B63_78g13 ⚠ Proteasome activator complex subunit 4	—	OG7 LdBPK_071090.1 ↔ LdBPK_240010.1	OG7
C4B63_78g10 ⚠ conserved hypothetical protein	—	OG7 LdBPK_071090.1 ↔ LdBPK_240010.1	OG7
C4B63_58g130 ⚠ vacuolar protein sorting-associated protein 3	—	OG7 LdBPK_210530.1 ↔ LdBPK_240010.1	OG7
C4B63_58g58 ⚠ conserved hypothetical protein	—	OG7 LdBPK_210240.1 ↔ LdBPK_240010.1	OG7
C4B63_58g59 ⚠ conserved hypothetical protein	—	OG7 LdBPK_210240.1 ↔ LdBPK_240010.1	OG7
C4B63_13g160 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002376	OG7
C4B63_183g17 ⚠ conserved hypothetical protein	—	OG7 LdBPK_040560.1 ↔ LdBPK_240010.1	OG7
C4B63_183g16 ⚠ conserved hypothetical protein	—	OG7 LdBPK_040560.1 ↔ LdBPK_240010.1	OG7
C4B63_38g148 ⚠ DENN (AEX-3) domain containing protein	—	OG7 LdBPK_040560.1 ↔ LdBPK_240010.1	OG7
C4B63_396g8 ⚠ synaptojanin (N-terminal domain)	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_007569 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_007569	OG7
C4B63_6g119 ⚠ oxidoreductase-like protein	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002566	OG7
C4B63_271g10 ⚠ conserved hypothetical protein	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005619	OG7
C4B63_45g121 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002376	OG7
C4B63_23g264 ⚠ 6-phosphofructo-2-kinase 1	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_002376	OG7
C4B63_13g1005c ⚠ peptidyl-prolyl cis-trans isomerase	—	OG7 TCSYLVIO_001571 ↔ TCSYLVIO_005957	OG7
C4B63_21g96 ⚠ conserved hypothetical protein	—	OG7 LdBPK_100740.1 ↔ LdBPK_240010.1	OG7
C4B63_85g75 ⚠ ubiquitin activating enzyme	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_010542	OG7

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