C4B63_58g59

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139114 OG7: OG7_0043219 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g765 ⚠
cystathione gamma lyase
— Both
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— Both
C4B63_4g140 ⚠
conserved hypothetical protein
— Both
C4B63_4g235 ⚠
5-oxoprolinase
— Both
C4B63_4g234 ⚠
5-oxoprolinase
— Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_186g6 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_22g11 ⚠
developmentally regulated phosphoprotein
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_21g96 ⚠
conserved hypothetical protein
— Both
C4B63_24g301 ⚠
phosphatidylinositol-4-phosphate 5-kinase
— OG7
C4B63_17g127 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_78g10 ⚠
conserved hypothetical protein
— OG7
C4B63_78g13 ⚠
Proteasome activator complex subunit 4
— OG7
C4B63_78g9 ⚠
conserved hypothetical protein
— OG7
C4B63_234g11 ⚠
conserved hypothetical protein
— OG7
C4B63_78g12 ⚠
conserved hypothetical protein
— OG7
C4B63_78g11 ⚠
conserved hypothetical protein
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_58g130 ⚠
vacuolar protein sorting-associated protein 3
— Both
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— Both
C4B63_1g48 ⚠
Deubiquitinase DESI2
— Both
C4B63_28g76 ⚠
Leucine-rich repeat-containing protein 9
— Both
C4B63_22g22 ⚠
ARM-like helical domain-containing protein
— OG6
C4B63_32g239 ⚠
tubulin folding cofactor D
— Both
C4B63_57g110 ⚠
conserved hypothetical protein
— Both
C4B63_28g93 ⚠
DeSI-like protein At4g17486
— Both
C4B63_2g731 ⚠
zinc-finger protein
— OG6
C4B63_22g23 ⚠
ARM-like helical domain-containing protein
— OG6
C4B63_6g400 ⚠
conserved hypothetical protein
— Both
C4B63_10g293 ⚠
Phosphatidylinositol 4-phosphate 5-kinase 6
— OG6
C4B63_235g21 ⚠
DeSI-like protein At4g17486
— Both
C4B63_2g368 ⚠
conserved hypothetical protein
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_23g186 ⚠
aspartyl aminopeptidase
— Both
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_43g141 ⚠
conserved hypothetical protein
— Both
C4B63_1g43 ⚠
DeSI-like protein At4g17486
— Both
C4B63_101g26 ⚠
conserved hypothetical protein
— Both
C4B63_282g21 ⚠
conserved hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.