C4B63_101g26

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147018 OG7: OG7_0042983 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g392 ⚠
ubiquitin hydrolase
— OG7
C4B63_31g177 ⚠
ribonuclease Z
— Both
C4B63_10g293
Phosphatidylinositol 4-phosphate 5-kinase 6
— OG6
C4B63_6g400 ⚠
conserved hypothetical protein
— Both
C4B63_282g21 ⚠
conserved hypothetical protein
— Both
C4B63_35g128 ⚠
ubiquitin hydrolase
— Both
C4B63_134g35 ⚠
ubiquitin hydrolase
— Both
C4B63_4g235 ⚠
5-oxoprolinase
— Both
C4B63_4g234 ⚠
5-oxoprolinase
— Both
C4B63_28g76
Leucine-rich repeat-containing protein 9
— Both
C4B63_26g275
protein phosphatase 2A regulatory subunit
— Both
C4B63_85g46 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g21 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g24 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_2g750
death-receptor fusion protein (DUF2428)
— Both
C4B63_18g156 ⚠
protein mkt1
— Both
C4B63_28g87 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_58g121 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_42g96 ⚠
ubiquitin hydrolase
— OG7
C4B63_61g132 ⚠
WD domain, G-beta repeat
— OG7
C4B63_24g301
phosphatidylinositol-4-phosphate 5-kinase
— OG7
C4B63_186g6 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_17g127 ⚠
Desumoylating isopeptidase 1
— OG7
C4B63_14g40
conserved hypothetical protein
— OG7
C4B63_17g55 ⚠
cyclin 9
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g391 ⚠
ubiquitin hydrolase
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_6g582
conserved hypothetical protein
— OG7
C4B63_79g39 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_97g26
conserved hypothetical protein
— OG7
C4B63_7g290 ⚠
RING finger protein ETP1
— OG7
C4B63_1g61 ⚠
conserved hypothetical protein
— OG7
C4B63_1g62 ⚠
conserved hypothetical protein
— OG7
C4B63_1g63 ⚠
SKP1
— OG7
C4B63_78g10 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.