C4B63_13g1005c

peptidyl-prolyl cis-trans isomerase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_109419 OG7: OG7_0001020 140 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 140 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_429g2 ⚠
leucine-rich repeat-containing protein
— OG7
C4B63_142g11 ⚠
Protein shuttle craft
— OG7
C4B63_25g257 ⚠
zinc-finger protein ZPR1
— OG7
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
C4B63_4g63 ⚠
polyprenyl synthase
— OG7
C4B63_30g184 ⚠
Basic immunoglobulin-like variable motif-cont
— OG7
C4B63_4g181 ⚠
Sestrin-3
— OG7
C4B63_25g188 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
C4B63_114g1 ⚠
N-acetyltransferase
— OG7
C4B63_51g180 ⚠
N-acetyltransferase complex ARD1 subunit
— OG7
C4B63_76g60 ⚠
N-acetyltransferase
— OG7
C4B63_8g52 ⚠
tRNA pseudouridine(31) synthase
— OG7
C4B63_83g79 ⚠
RNA pseudouridylate synthase
— OG7
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_6g119 ⚠
oxidoreductase-like protein
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_56g69 ⚠
CYC2-like cyclin
— OG7
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— OG7
C4B63_18g174 ⚠
cyclin
— OG7
C4B63_23g85 ⚠
leucine-rich repeat-containing protein
— OG7
C4B63_3g553 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— OG7
C4B63_2g244 ⚠
conserved hypothetical protein
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_101g21 ⚠
conserved hypothetical protein
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_20g12 ⚠
Vacuolar protein sorting-associated protein 2
— OG7
C4B63_44g117 ⚠
conserved hypothetical protein
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_42g201 ⚠
conserved hypothetical protein
— OG7
C4B63_15g18 ⚠
NADH-dependent fumarate reductase
— OG7
C4B63_34g375 ⚠
Soluble NSF attachment protein, SNAP (parafla
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_14g27 ⚠
flagellum transition zone component
— OG7
C4B63_17g63 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_42g49 ⚠
Protein aardvark
— OG7
C4B63_40g52 ⚠
conserved hypothetical protein
— OG7
C4B63_22g11 ⚠
developmentally regulated phosphoprotein
— OG7
C4B63_7g377 ⚠
[Pyruvate dehydrogenase (acetyl-transferring)
— OG7
C4B63_12g234 ⚠
protein transport protein Sec31
— OG7
C4B63_30g203 ⚠
conserved hypothetical protein
— OG7
C4B63_25g202 ⚠
conserved hypothetical protein
— OG7
C4B63_25g203 ⚠
conserved hypothetical protein
— OG7
C4B63_8g522 ⚠
conserved hypothetical protein
— OG7
C4B63_12g235 ⚠
protein transport protein Sec31
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.