C4B63_8g52

tRNA pseudouridine(31) synthase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_141873 OG7: OG7_0001865 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_171g30 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_45g128 ⚠
conserved hypothetical protein
— OG7
C4B63_45g130 ⚠
conserved hypothetical protein
— OG7
C4B63_45g129 ⚠
conserved hypothetical protein
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_21g264 ⚠
protein transport protein SEC23
— OG7
C4B63_4g63 ⚠
polyprenyl synthase
— OG7
C4B63_114g1 ⚠
N-acetyltransferase
— OG7
C4B63_76g60 ⚠
N-acetyltransferase
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_4g494 ⚠
conserved hypothetical protein
— OG7
C4B63_49g325c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_44g117 ⚠
conserved hypothetical protein
— OG7
C4B63_44g113 ⚠
conserved hypothetical protein
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_157g28 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
C4B63_22g77 ⚠
conserved hypothetical protein
— OG7
C4B63_13g1005c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_17g63 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_19g86 ⚠
CYC2-like cyclin 6
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_18g174 ⚠
cyclin
— OG7
C4B63_56g69 ⚠
CYC2-like cyclin
— OG7
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_17g182 ⚠
phosphatidylinositol 3-kinase catalytic subun
— OG7
C4B63_42g49 ⚠
Protein aardvark
— OG7
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— OG7
C4B63_14g27 ⚠
flagellum transition zone component
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_20g49 ⚠
conserved hypothetical protein
— OG7
C4B63_44g114 ⚠
conserved hypothetical protein
— OG7
C4B63_4g181 ⚠
Sestrin-3
— OG7
C4B63_58g128 ⚠
conserved hypothetical protein
— OG7
C4B63_22g94 ⚠
cyclophilin 15
— OG7
C4B63_19g179 ⚠
protein kinase
— OG7
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— OG7
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_4g509 ⚠
FKBP-type peptidylprolyl cis-trans isomerase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.