C4B63_19g179

protein kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101388 OG7: OG7_0005083 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g244 ⚠
conserved hypothetical protein
— Both
C4B63_2g243 ⚠
conserved hypothetical protein
— Both
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— +1 more Both
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_25g215 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_25g214 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_11g473
DNL-type zinc finger protein
— OG7
C4B63_44g117
conserved hypothetical protein
— OG7
C4B63_42g201
conserved hypothetical protein
— OG7
C4B63_2g798 ⚠
Putative pentatricopeptide repeat-containing
— OG7
C4B63_25g241
conserved hypothetical protein
— OG7
C4B63_14g48 ⚠
rab-like GTPase activating protein
— OG7
C4B63_42g216 ⚠
disgorgin
— OG7
C4B63_35g171 ⚠
tRNA (guanine(37)-N1)-methyltransferase 1
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_12g22
conserved hypothetical protein
— OG7
C4B63_40g73 ⚠
glycosyl hydrolase-like protein
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_93g64 ⚠
amidohydrolase
— OG7
C4B63_136g37 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG7
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_8g211 ⚠
cytochrome b
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_25g1526c ⚠
Acyl-lipid (8-3)-desaturase
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_2g564 ⚠
mRNA export factor MEX67
— OG7
C4B63_47g107 ⚠
ABC transporter
— OG7
C4B63_26g317 ⚠
Alanyl-tRNA editing protein Aarsd1-B
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_136g36 ⚠
Alanyl-tRNA editing protein Aarsd1
— OG7
C4B63_113g34 ⚠
ABC transporter
— OG7
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_425g4 ⚠
tyrosyl or methionyl-tRNA synthetase
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.