C4B63_35g171

tRNA (guanine(37)-N1)-methyltransferase 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100981 OG7: OG7_0003743 132 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 132 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g21 ⚠
Uncharacterized oxidoreductase YkwC
— OG7
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_93g64 ⚠
amidohydrolase
— Both
C4B63_18g219 ⚠
tRNA methyltransferase 10 homolog A
— Both
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_32g257 ⚠
Cyclin-U3-1
— Both
C4B63_8g522 ⚠
conserved hypothetical protein
— Both
C4B63_2g564 ⚠
mRNA export factor MEX67
— Both
C4B63_16g147 ⚠
Ring finger domain containing protein
— OG6
C4B63_259g22 ⚠
Ring finger domain containing protein
— OG6
C4B63_95g48 ⚠
protein kinase
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_23g116 ⚠
Importin beta-like SAD2
— OG7
C4B63_101g25 ⚠
acid phosphatase
— OG7
C4B63_181g13 ⚠
conserved hypothetical protein
— OG7
C4B63_25g968c ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_34g156 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_7g1820c ⚠
acyl-CoA binding protein
— OG7
C4B63_109g69 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_61g73 ⚠
Acyl-CoA-binding domain-containing protein 5
— OG7
C4B63_30g132 ⚠
ubiquitin activating enzyme
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_49g325c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_44g117 ⚠
conserved hypothetical protein
— OG7
C4B63_83g79 ⚠
RNA pseudouridylate synthase
— OG7
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_13g189 ⚠
ubiquitin-like protein
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_14g27 ⚠
flagellum transition zone component
— OG7
C4B63_19g86 ⚠
CYC2-like cyclin 6
— OG7
C4B63_4g502 ⚠
ABC transporter
— OG7
C4B63_17g63 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_19g259 ⚠
conserved hypothetical protein
— OG7
C4B63_46g15 ⚠
Kinesin-13 5
— OG7
C4B63_69g61 ⚠
Kinesin-13 1
— OG7
C4B63_44g235 ⚠
Kinesin-13 4
— OG7
C4B63_144g30 ⚠
Kinesin-13 1
— OG7
C4B63_76g60 ⚠
N-acetyltransferase
— OG7
C4B63_114g1 ⚠
N-acetyltransferase
— OG7
C4B63_13g1005c ⚠
peptidyl-prolyl cis-trans isomerase
— OG7
C4B63_325g1 ⚠
Kinesin-13 1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.